Results 81 to 90 of about 91,982 (303)

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Large-Scale Simulations of Clusters of Galaxies

, 2000
We discuss some of the computational challenges encountered in simulating the evolution of clusters of galaxies. Eulerian adaptive mesh refinement (AMR) techniques can successfully address these challenges but are currently being used by only a few ...
Calder, A. C., Dursi, L. J., Fryxell, B., Lamb, D. Q., MacNeice, P., Olson, K., Ricker, P. M., Rosner, R., Timmes, F. X., Truran, J. W., Tufo, H. M., Zingale, M.   +11 more
core   +2 more sources

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Numerical Analysis of Fluid‒solid Interactions in a 3D Piezoelectric Micropump Featuring a Passive Check Valve [PDF]

Journal of Applied Fluid Mechanics
Piezoelectric micropumps have attracted considerable research attention due to their low production cost, compact size, and controllable output performance.
Y. F. Zhang, B. Zhou, Z. L. Deng
doaj   +1 more source

Ultra directive antenna via transformation optics

, 2009
Spatial coordinate transformation is used as a reliable tool to control electromagnetic fields. In this paper, we derive the permeability and permittivity tensors of a metamaterial able to transform an isotropically radiating source into a compact ...
Burokur, Shah Nawaz, de Lustrac, Andre, Tichit, Paul-Henri   +2 more
core   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

The Actuator Design and the Experimental Tests of a New Technology Large Deformable Mirror for Visible Wavelengths Adaptive Optics

, 2012
Recently, Adaptive Secondary Mirrors showed excellent on-sky results in the Near Infrared wavelengths. They currently provide 30mm inter-actuator spacing and about 1 kHz bandwidth.
Agapito, Guido, Arcidiacono, Carmelo, Biliotti, Valdemaro, Carbonaro, Luca, De Santis, Enzo, Del Vecchio, Ciro, Marignetti, Fabrizio, Riccardi, Armando   +7 more
core   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Finite Element Modelling of Coupled Fluid-Flow and Geomechanical Aspects for the Sustainable Exploitation of Reservoirs: The Case Study of the Cavone Reservoir

Geosciences, 2019
The study of the seismogenic mechanical effects induced by oil & gas activities is a socially impacting issue of environmental engineering as well as a challenging task in computational geomechanics.
Elena Benvenuti, Giulia Maurillo
doaj   +1 more source

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source