Results 61 to 70 of about 1,958,932 (291)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
An Enhanced Precoder for Multi User Multiple-Input Multiple-Output Downlink Systems
Applied Sciences, 2020 Recently, as the demand for data rate of users has increased, wireless communication systems have aimed to offer high throughput. For this reason, various techniques which guarantee high performance have been invented, such as massive multiple-input ...
Woon-Sang Lee +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Monotonicity Results for Coherent MIMO Rician Channels [PDF]
, 2005 The dependence of the Gaussian input information rate on the line-of-sight (LOS) matrix in multiple-input multiple-output coherent Rician fading channels is explored.
Hoesli, Daniel +2 more
core +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A High-Diversity Transceiver Design for MISO Broadcast Channels
, 2019 In this paper, the outage behavior and diversity order of the mixture transceiver architecture for multiple-input single-output broadcast channels are analyzed.
Jafarkhani, Hamid +2 more
core +3 more sources
Multiple‐input–multiple‐output cooperative spatial modulation systems
IET Communications, 2017 In this study, the authors propose novel cooperative spatial modulation (SM) systems with two main relaying techniques [amplify‐and‐forward (AF) and decode‐and‐forward (DF)], where all nodes have multiple transmit and/or receive antennas.
Gökhan Altin +3 more
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source