Results 21 to 30 of about 13,411 (215)

Selection and Solving it with Genetic Algorithms [PDF]

چشم‌انداز مدیریت صنعتی, 2017
In the selection of a collection of investment assets, the expected utility of investor is determined via risk and return criteria. Regarding the uncertainty of the investor about the future, portfolio diversification is a common path towards risk ...
Moslem Khakbiz, Abbas Rezaei Pandari, Mahmoud Dehghan Nayeri   +2 more
doaj  

An Efficient Variable Neighborhood Search for Solving Multi-Criteria Project Portfolio Selection [PDF]

Control and Optimization in Applied Mathematics
Project portfolio selection is a critical challenge for many organizations as they often face budget constraints that limit their ability to support all available projects. To address this issue, organizations seek to select a feasible subset of projects
Ali Akbar Sohrabi, Reza Ghanbari, Khatere Ghorbani-Moghadam   +2 more
doaj   +1 more source

Analytical Shortcuts to Multiple-Objective Portfolio Optimization: Investigating the Non-Negativeness of Portfolio Weight Vectors of Equality-Constraint-Only Models and Implications for Capital Asset Pricing Models

Mathematics
Computing optimal-solution sets has long been a topic in multiple-objective optimization. Despite substantial progress, there are still research limitations in the multiple-objective portfolio optimization area.
Yue Qi, Yue Wang, Jianing Huang, Yushu Zhang   +3 more
doaj   +1 more source

Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory [PDF]

تحقیقات مالی
ObjectiveThe optimization of asset portfolios, taking into account market advancements, has emerged as a pivotal subject in financial economics. Constructing asset portfolios is acknowledged as a critical decision for investors. Consequently, researchers
vahideh mousavi kakhki, Sanaz Khatabi
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

RETHINKING MULTI-ASSET PORTFOLIO OPTIMISATION FOR A TURBULENT BUSINESS ENVIRONMENT: NEW INSIGHTS [PDF]

Academy Review
Financial asset portfolio optimisation is the primary objective of all fund managers managing multiple asset classes for international investors. Multi-asset portfolios across global markets are regarded as well-rounded financial portfolios.
Nupur Gupta, Ayush Agrawalb, Vivek Choukseyc   +2 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source