Results 201 to 210 of about 2,860,766 (265)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

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Multiple resource multiple access algorithms

IEEE Transactions on Communications, 1995
Two distributed multiple resource/multiple access algorithms, the receiver oriented protocol (ROP) and the dependent receiver oriented protocol (DROP), that are applicable to mobile networks connected by point-to-point radio or satellite links are presented and the maximum throughput is determined.
J. Capetanakis, T. Altes
openaire   +1 more source

Multiple access communications networks

IEEE Communications Magazine, 1987
An introduction is provided to multiple-access communications networks in which the terminals share common communications channels. These networks include satellite networks, local area networks, and packet radio networks. Various multiple-access protocols are described, and it is shown how some of them are used in different multiple-access networks.
openaire   +2 more sources

Multiple access modulation techniques

Communications Satellite Systems Conference, 1966
Abstract This paper quantitatively and qualitatively compares the following multiple-access satellite communication techniques: frequency-division multiple access (FDMA), time-division multiple access (TDMA), spread-spectrum multiple access (SSMA), and pulse-address multiple access (PAMA).
openaire   +1 more source

Power division multiple access

ICUPC '98. IEEE 1998 International Conference on Universal Personal Communications. Conference Proceedings (Cat. No.98TH8384), 2002
This paper presents and analyzes a new multiple access scheme, which is power diversity based, for an asynchronous environment. The key idea is to have different received power for each user in order to permit successive reception based on cochannel interference cancellation.
openaire   +1 more source

Random Access Versus Multiple Access

2018
The support of Internet of Things (IoT) calls for physical and media access control (MAC) solutions capable to support a very large number of wireless devices transmitting short packets with low duty cycle. This chapter provides a survey of random access (RA) schemes devised for terrestrial and satellite applications which are suited to support IoT ...
Riccardo De Gaudenzi, Oscar del Río Herrero, Stefano Cioni, Alberto Mengali   +3 more
openaire   +1 more source

Multiple Access Alternatives

2004
Thus far in this book we have discussed the signal processing necessary for digital communications from one point to another over a communications medium. The remainder of the book will begin to address the realization of a digital communications network in which many users simultaneously communicate with one another. One of the key issues that must be
John R. Barry, Edward A. Lee, David G. Messerschmitt   +2 more
openaire   +1 more source

Multiple Access Techniques

2020
Multiple access is an essential physical-layer technique in wireless communication networks that allows multiple mobile users to access the network simultaneously. Driven by the upsurge of devices expected in 6G and beyond, future wireless communication networks are foreseen to operate in dynamic regimes ranging from underloaded (where the number of ...
Yijie Mao, Bruno Clerckx
openaire   +1 more source