Results 71 to 80 of about 494,961 (258)

Mitigation of Optical Interference Noise by Optical Carrier Cancelation in Self-Coherent Reflective PON Uplink Transmission

open access: yesIEEE Photonics Journal, 2017
Optical interference noise (OIN), including optical beating interference and Rayleigh back-scattering noise, severely degrades transmission performance in self-coherent reflective passive optical network uplink transmission systems.
Soo-Min Kang   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Partially Overlapping NOMA System with Many Neighboring Channels

open access: yesJournal of Communications Software and Systems
The increasing usage of the Internet of Things (IoT) and other modern massive machine-type communication applications has led to a growing demand for more efficient u tilization o f a vailable c ommunication bandwidth.
Zoltán Belso, László Pap
doaj   +1 more source

Cochannel interference cancelation for multiple access systems

open access: yesJournal of Systems Engineering and Electronics, 2007
Abstract Many properties of frequency-hopped spread-spectrum multiple access (FH/SSMA), such as, robust-ness against frequency selective fading and jamming make it a preferred multiple access communication scheme. But cochannel interference (CCI) can seriously harm the system's performance. On the basis of the analysis of the CCI pattern of frequency
Wang Xia, Zhu Shihua, Sun Delong
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Performance Analysis of the New Flexible Double Weight (FDW) Code With Various Detection Techniques

open access: yesIEEE Access
In this paper, Spectral Amplitude Coding Optical Code Division Multiple Access (SAC-OCDMA) system performance is analyzed using a Flexible Double Weight (FDW) code with various detection techniques. In theoretical analysis, various types of noise such as
Muhammad Amirul Anuar   +6 more
doaj   +1 more source

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