Results 71 to 80 of about 550,503 (292)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Linguistic Picture Fuzzy Dombi Aggregation Operators and Their Application in Multiple Attribute Group Decision Making Problem

Mathematics, 2019
The aims of this study are to propose the linguistic picture fuzzy Dombi (LPFD) aggregation operators and decision-making approach to deal with uncertainties in the form of linguistic picture fuzzy sets.
Muhammad Qiyas, Saleem Abdullah, Shahzaib Ashraf, Lazim Abdullah   +3 more
doaj   +1 more source

Open source environment to define constraints in route planning for GIS-T [PDF]

, 2004
Route planning for transportation systems is strongly related to shortest path algorithms, an optimization problem extensively studied in the literature.
Pérez Vidal, Lluís, Silveira, A. da Mota   +1 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An Approach to Multiple Attribute Group Decision Making Based on Intuitionistic Trapezoidal Fuzzy Power Generalized Aggregation Operator [PDF]

International Journal of Computational Intelligence Systems, 2014
With respect to multiple attribute decision making (MADM) problems in which the attribute value takes the form of intuitionistic trapezoidal fuzzy number, a new decision making analysis method is developed.
Peide Liu, Ying Liu
doaj   +1 more source

Incremental learning of independent, overlapping, and graded concept descriptions with an instance-based process framework [PDF]

, 1989
Supervised learning algorithms make several simplifying assumptions concerning the characteristics of the concept descriptions to be learned. For example, concepts are often assumed to be (1) defined with respect to the same set of relevant attributes ...
Aha, David W.
core  

Consensus Rules with Minimum Adjustments for Multiple Attribute Group Decision Making

Procedia Computer Science, 2013
AbstractIn this study, we propose two optimization-based consensus rules, called consensus rules with minimum adjustments, for multiple attribute group decision making (MAGDM) problems. One of these two consensus rules is to minimize the distance between the original and adjusted preferences, and the other one seeks to minimize the number of adjusted ...
Zhang, Bowen, Dong, Yucheng
openaire   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source