Results 71 to 80 of about 18,011,088 (290)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Modelling and optimizing multiple attribute decisions by using fuzzy sets [PDF]

open access: yes
The purpose of this paper is to present a coherent perspective of modeling and optimizing multiple attribute decisions by using fuzzy sets. In management practice we face most of the time the situation in which a problem have several possible solutions ...
Adina NEGRUSA, Gh. Gh. IONESCU
core  

Probabilistic Linguistic Multiple Attribute Group Decision-Making Based on a Choquet Operator and Its Application in Supplier Selection

open access: yes
As an enhanced version of traditional linguistic term sets, Probabilistic Linguistic Term Sets (PLTS) incorporate probabilistic information, thereby offering a more robust approach to Multiple Attribute Group Decision-Making (MAGDM) and significantly ...
Xin Liang, Weijia Kang, Yan Peng
core   +1 more source

Q-Rung Probabilistic Dual Hesitant Fuzzy Sets and Their Application in Multi-Attribute Decision-Making

open access: yes, 2020
The probabilistic dual hesitant fuzzy sets (PDHFSs), which are able to consider multiple membership and non-membership degrees as well as their probabilistic information, provide decision experts a flexible manner to evaluate attribute values in ...
Jun Wang, Hegong Lei, Li Li
core   +1 more source

Bonferroni Mean Operators of Linguistic Neutrosophic Numbers and Their Multiple Attribute Group Decision-Making Methods

open access: yesInformation, 2017
Linguistic neutrosophic numbers (LNN) is presented by Fang and Ye in 2017, which can describe the truth, falsity, and indeterminacy linguistic information independently.
Changxing Fan, Jun Ye, Keli Hu, En Fan
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Multiple criteria decision making

open access: yes, 1973
817 p., fig., ref. bib. : 17 p.1/2This volume is the direct result of a seminar on Multiple Criteria Decision Making held at the University of South Carolina on October 26-27, 1972. Support for this seminar and for production of this book was provided by
ZELENY, Milan, COCHRANE, James L.
core  

Critical review of multi-criteria decision aid methods in conceptual design phases: application to the development of a solar collector structure [PDF]

open access: yes, 2014
At each stage of the product development process, the designers are facing an important task which consists of decision making. Two cases are observed: the problem of concept selection in conceptual design phases and, the problem of pre-dimensioning once
EL AMINE, Mehdi   +3 more
core   +1 more source

Linguistic Intuitionistic Fuzzy Hamy Mean Operators and Their Application to Multiple-Attribute Group Decision Making

open access: yesIEEE Access, 2019
The Hamy Mean (HM) operator is a useful aggregation tool characterized by considering the correlation between multiple integral parameters. The linguistic intuitionistic fuzzy numbers (LIFNs) use linguistic variables (LVs) to represent membership degree (
Peide Liu, Xiaoxiao Liu
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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