Results 201 to 210 of about 714,112 (258)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Increases in One-year Mortality Risk Among Chronic Skin Ulcer Patients During the Period 1980-2020. [PDF]

open access: yesActa Derm Venereol
Salenius JE   +4 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Predictors of perioperative mortality in children undergoing surgery at a Nigerian tertiary hospital: insights from Sagamu. [PDF]

open access: yesWorld J Pediatr Surg
Amosu LO   +9 more
europepmc   +1 more source

What is not measured cannot be improved: the urgency to understand causes of HIV-related deaths in Latin America. [PDF]

open access: yesJ Int AIDS Soc
Lopez-Villalba B   +4 more
europepmc   +1 more source

Two Approaches for Comparing Characteristics of Decedents With Sickle Cell Disease: Inconsistencies and Implications. [PDF]

open access: yesPublic Health Rep
Attell BK   +7 more
europepmc   +1 more source

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