Results 61 to 70 of about 1,787,467 (299)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Revista Brasileira de Epidemiologia, 2000 Uma das possibilidades permitidas pelo avanço tecnológico é o estudo da mortalidade por causas múltiplas em contraposição à estatística feita por uma única causa, a chamada causa básica de morte.
Ruy Laurenti, Cássia Maria Buchalla
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Weighted Mortality Method According to Multiple Causes of Death
Revista Finlay, 2019 Foundation: mortality study usually shows death as a single-caused phenomenon, so it is considered necessary to discuss methods which include in the analysis, all diseases recorded in medical death certificates.
Lisbeth Fernández González +2 more
doaj +2 more sources
Multiple causes of death related to Chagas' disease in Brazil, 1999 to 2007
Revista da Sociedade Brasileira de Medicina Tropical, 2012 INTRODUCTION: Chagas' disease is a major public health problem in Brazil and needs extensive and reliable information to support consistent prevention and control actions.
Francisco Rogerlândio Martins-Melo +3 more
doaj +1 more source
Rates and Causes of Death in Chiradzulu District, Malawi, 2008: A Key Informant Study [PDF]
, 2010 In September 2008, we measured all-cause mortality in Chiradzulu District, Malawi (population 291 000) over a 60-day retrospective period, using capture-recapture analysis of three lists of deaths provided by (i) key community informants, (ii) graveyard ...
Adjuik +10 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bayesian joint spatio-temporal analysis of multiple diseases [PDF]
, 2019 In this paper we propose a Bayesian hierarchical spatio-temporal model for the joint analysis of multiple diseases which includes specific and shared spatial and temporal effects.
Fernández-Navarro, Pablo +4 more
core
Validation of a classification system for treatment-related mortality in children with cancer [PDF]
, 2017 Background Death not directly due to cancer has been termed 'treatment-related mortality' (TRM). Appreciating the differences between TRM and disease-related death is critical in directing strategies to improve supportive care, interventions delivered or
Alexander +7 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source