Results 71 to 80 of about 1,232,214 (293)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Computer-based pre-clinical assessment [Computer-gestütztes Prüfen im 1. Studienabschnitt]
GMS Zeitschrift für Medizinische Ausbildung, 2006 [english] According to the new German Federal Regulations for medical education, the written preclinical national boards examination ("1. Staatsexamen") should focus on - a horizontal integration of all subjects - a vertical link through clinical ...
Fischer, Martin R., Kopp, Veronika
doaj
Basic principles of constructing multiple choice questions
Indian Journal of Community and Family Medicine, 2015 Multiple Choice Questions (MCQs) are one of the most important well established tools used for assessment and selection processes in medical education.
Sitanshu Sekhar Kar +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Multiple-choice versus short-response items: Differences in omit behavior
, 1999 The overall rate of omission of items for 28,331 17 year old Australian students on a high stakes test of achievement in the common elements or cognitive skills of the senior school curriculum is reported for a subtest in multiple choice format and a ...
Matters, Gabrielle, Burnett, Paul C.
core
Item Response Models for Forced-Choice Questionnaires: A Common Framework [PDF]
, 2016 In forced-choice questionnaires, respondents have to make choices between two or more items presented at the same time. Several IRT models have been developed to link respondent choices to underlying psychological attributes, including the recent MUPP ...
Brown, Anna
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Latent Thresholds Analysis of Choice Data with Multiple Bids and Response Options [PDF]
In many stated preference settings stakeholders will be uncertain as to their exact willingness-to-pay for a proposed environmental amenity. To accommodate this possibility analysts have designed elicitation formats with multiple bids and response ...
Klaus Moeltner +2 more
core
TES KETERAMPILAN PROSES SAINS: MULTIPLE CHOICE FORMAT
Jurnal Pendidikan Sains Universitas Muhammadiyah Semarang, 2019 The purpose of this study was to develop and validate a multiple choice science process skills test. This research was a mixed method using sequential exploratory design. The data collection phase was divided into two.
Fibrika Rahmat Basuki +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source