Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
A multiple criteria framework for value-based assessment of health care services applied to a radiology case. [PDF]
Moreira A, Rego N, Crispim J.
europepmc +1 more source
Supporting contaminated sites management with Multiple Criteria Decision Analysis: Demonstration of a regulation-consistent approach. [PDF]
Cinelli M +6 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Disentangling complex relationships and disjunctions in western Camassia: Integrating multiple criteria to resolve taxonomic boundaries. [PDF]
Kephart SR +5 more
europepmc +1 more source
Multiple Criteria Decision Analysis (MCDA) for evaluating cancer treatments in hospital-based health technology assessment: The Paraconsistent Value Framework. [PDF]
Campolina AG +3 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Using multiple criteria for redesigning habitat corridor plans for Giant Pandas. [PDF]
Diao Y +8 more
europepmc +1 more source
Developing a novel stock index trend predictor model by integrating multiple criteria decision-making with an optimized online sequential extreme learning machine. [PDF]
Samal S, Dash R.
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source

