Results 71 to 80 of about 9,009,703 (255)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Examples of Objectified Multiple Criteria Ranking in the Selection of Infrastructural Projects

Journal of Telecommunications and Information Technology, 2018
The paper addresses the issue of multiple criteria rankings of infrastructural projects (buildings, roads, etc.). Although the amount of literature devoted to this subject is considerable, all methods proposed produce subjective rankings, dependent on a
Edward Klimasara, Andrzej Piotr Wierzbicki   +1 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Multi-Criteria Framework for Routing on Access Land: A Case Study on Dartmoor National Park

ISPRS International Journal of Geo-Information
Creating routes across open areas is challenging due to the absence of a defined routing network and the complexity of the environment, in which multiple criteria may affect route choice.
Rafael Felipe Sprent, James Haworth, Stefano Cavazzi, Ilya Ilyankou   +3 more
doaj   +1 more source

Evaluating the changes in economic and social development of Lithuanian counties by multiple criteria methods

Technological and Economic Development of Economy, 2009
Under the conditions of the country's economy restructurization, the differences between economic and social development of various regions are becoming more prominent. To smooth these differences, a number of scientific and practical problems associated
Romualdas Ginevičius, Valentinas Podvezko   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Radiologically isolated syndrome and multiple sclerosis [PDF]

, 2017
Background Incidental white matter lesions (WML) are increasingly seen on brain magnetic resonance imaging (MRI) in clinical practice. Demyelination consistent with MS is seen in 0.1–0.7% of the population as evident by autopsy and MRI studies.
AlKhawajah, Mona Marwan, B. Yamout, M. Al Khawajah, Yamout, Bassem I.   +3 more
core   +1 more source

Capital Budgeting: Multiple Criteria [PDF]

Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2008
In this article, we propose a model that incorporates the preference of multiple decision makers in to a decision making process using multiple criteria and cardinal method in the capital budgeting context.
Maryam Khalili Araghi
doaj  

Multiple criteria assessment of high-rise timber buildings

Engineering Structures and Technologies, 2019
Although the majority of high-rise buildings are constructed from concrete and steel, there is a growing interest in the new generation of multi-storey timber buildings around the world and several ecologically sustainable structural systems have already
Laura Tupėnaitė, Viktorija Žilėnaitė, Loreta Kanapeckienė, Seyed Masoud Sajjadian, Tomas Gečys, Lina Sakalauskienė, Jurga Naimavičienė   +6 more
doaj   +1 more source