Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Hybrid Multiple-Criteria Decision-Making Model for Home Healthcare Nurses' Job Satisfaction Evaluation and Improvement. [PDF]
Int J Public Health, 2022 Wang Y +5 more
europepmc +1 more source
Decision support for information systems management : applying analytic hierarchy process [PDF]
Decision-making in the field of information systems has become more complex due to a larger number of alternatives, multiple and sometimes conflicting goals, and an increasingly turbulent environment.
Huizingh, Eelko K.R.E. +1 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Neutrosophic Soft Expert Multiset and Their Application to Multiple Criteria Decision Making
Mathematics, 2019 In this paper, we have investigated neutrosophic soft expert multisets (NSEMs) in detail. The concept of NSEMs is introduced. Several operations have been defined for them and their important algebraic properties are studied.
Derya Bakbak +2 more
doaj +1 more source
Multiple Criteria Decision Making: Method Selection And Application To Three Contrasting Agricultural Case Studies [PDF]
Agribusiness, farm business and agricultural-environmental decisions which varied in their characteristics were used to evaluate multiple criteria decision making (MCDM) in an agricultural context.
Dooley, A.E. +2 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A MapReduce-Based Decision-Making Approach for Multiple Criteria Sorting
SystemsIn the context of big data and artificial intelligence, analyzing and extracting actionable insights from extensive datasets to enhance decision-making processes presents both intriguing opportunities and formidable challenges. Existing multiple criteria
Xiaoxin Mao, Zhanhe Du, Lanlan Zheng
doaj +1 more source
Complex T-spherical fuzzy Dombi aggregation operators and their applications in multiple-criteria decision-making. [PDF]
Complex Intell Systems, 2021 Karaaslan F, Dawood MAD.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source