Results 261 to 270 of about 792,799 (305)
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Multiple Drug Resistance Mechanisms in Cancer
Molecular Biotechnology, 2010Multiple drug resistance (multidrug resistance; MDR), a phenomenon whereby human tumours that acquire resistance to one type of therapy are found to be resistant to several other drugs that are often quite different in both structure and mode of action, has been recognised clinically for several decades. An important advance in our understanding of MDR
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Molecular cytogenetics of multiple drug resistance
Cytotechnology, 1993The refractory nature of many human cancers to multi-agent chemotherapy is termed multidrug resistance (MDR). In the past several decades, a major focus of clinical and basic research has been to characterize the genetic and biochemical mechanisms mediating this phenomenon.
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Drug resistance and drug development in multiple myeloma
Seminars in Oncology, 2002Circumvention of drug resistance in multiple myeloma is a major obstacle to improving clinical outcomes for myeloma patients. Identification of several mechanisms of acquired drug resistance has led to the development of chemosensitizing agents that counter specific drug resistance mechanisms.
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Transmissible Drug-resistance Factors and Formation of Multiple Resistance
Nature, 1962IN earlier reports several types of drug (chloramphenicol, Cm; tetracycline, Tc; streptomycin, Sm; sulphanilamide, Da) resistant Escherichia coli and Shigella were described1–3. It was also found that seven types of drug resistance are transmitted by cell-to-cell contact4.
S, MITSUHASHI, K, HARADA
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Drug resistance in multiple myeloma.
Pathologie-biologie, 1999Multidrug resistance (MDR) is a pleiotropic resistance against several unrelated drugs. It may be induced by prolonged exposure of cells to drugs such as doxorubicin, etoposide and vinca alkaloids. Once MDR develops in clinical tumors, it is a major obstacle for the improvement of treatment of multiple myeloma (MM).
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
exaly
Multiple-Drug-Resistant Salmonella typhi
Clinical Infectious Diseases, 1993A S, Mourad +8 more
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Decreasing multiple drug-resistant organisms
Heart & Lung, 2011Patricia W, Stone, Elaine, Larson
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MULTIPLE-DRUG-RESISTANT TUBERCULOSIS
The Pediatric Infectious Disease Journal, 1995HEINZ F. EICHENWALD, R. F. Jacobs
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