Results 271 to 280 of about 2,245,687 (336)
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MULTIPLE PATHWAY DRUG-RESISTANCE (REVIEW)
International Journal of Oncology, 1993During the past few years it has become apparent that multiple mechanisms of resistance are playing a role in the clinical manifestations of drug resistance. In different organs and tumors, various components of the resistance phenotype are expressed to varying degrees.
J, Mattern, M, Volm
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Directed Graphene-Based Nanoplatforms for Hyperthermia: Overcoming Multiple Drug Resistance.
Angewandte Chemie, 2018Multidrug resistance (MDR), which leads tumors resistance to traditional anticancer drugs, can cause the failure of chemotherapy treatments. Herein, we present a new way to overcome this problem using smart multifunctional graphene-based drug delivery ...
Zhaoxu Tu +6 more
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Overcoming multiple drug resistance in cancer using polymeric micelles
Expert Opinion on Drug Delivery, 2018Introduction: A major concern that limits the success of cancer chemotherapy is multidrug resistance (MDR). The drug resistance mechanisms are either host related or tumor related.
S. S. Kesharwani +3 more
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Multiple drug resistance inAerobacter aerogenes
Antonie van Leeuwenhoek, 1967Multiple drug resistance resulting from continued growth in various drugs in turn followed by serial subculture in the simultaneous presence of all the drugs has been studied. In this way strains ofA. aerogenes resistant, in considerable measure, to 3, 4 and 5 drugs have been obtained.
P G, Bolton, A C, Dean, P J, Rodgers
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Infectious Diseases - Drug Targets, 2023
The increased spreading of antibiotic resistance among different infectious agents has been a fast-growing public health challenge worldwide; this is because of the discovery of new resistance mechanisms and the reduction in quality and effective ...
J. A. Alara, O. R. Alara
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The increased spreading of antibiotic resistance among different infectious agents has been a fast-growing public health challenge worldwide; this is because of the discovery of new resistance mechanisms and the reduction in quality and effective ...
J. A. Alara, O. R. Alara
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Multiple-Drug-Resistant Tuberculosis
Clinical Infectious Diseases, 1994The modern era of tuberculosis recently has been characterized by a rise in the number of cases of infection with multiple-drug-resistant (MDR) Mycobacterium tuberculosis. This acquisition of resistance to various established antituberculosis drugs has compromised both treatment and control programs worldwide.
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Multiple drug resistance and intermediate filaments
Cancer and Metastasis Review, 1996One major obstacle to the successful treatment of epithelial derived tumors, such as breast and prostate carcinoma, is the presence of a multiple drug resistance phenotype. The drug resistance which is observed in growing epithelial derived cancer cells could either be an intrinsic, selected and/or an acquired characteristic.
A E, Cress, W S, Dalton
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Multiple drug resistance, antimutagenesis and anticarcinogenesis
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005Many cells are protected from excess levels of exogenous chemicals, including mutagens and carcinogens as well as pharmaceutical agents, by being actively extruded through the action of one or more of a series of ATP-binding cassette drug transporter proteins. Those known to be important in humans are the multidrug resistance proteins (P-glycoproteins,
L. R. FERGUSON, DE FLORA, SILVIO
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Topoisomerase II in multiple drug resistance
Cytotechnology, 1993Topoisomerase II is a target of alkaloid, anthracycline and related antitumor agents. Two types of multiple drug resistance are associated with these enzymes. In classical (typical) multidrug resistance, inhibitors are actively effluxed from cells by P-glycoprotein.
G A, Hofmann, M R, Mattern
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Role of nanomaterials in deactivating multiple drug resistance efflux pumps - A review.
Environmental Research, 2021Nibedita Dey +7 more
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