Results 121 to 130 of about 38,029,237 (226)
Genomic Medicine Sweden: Advancing precision medicine at the national level
Journal of Internal Medicine, Volume 300, Issue 4, Page 397-419, October 2026.Abstract
High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist +58 morewiley +1 more sourceSurvival and Mortality Predictors in Prostate Cancer: A Retrospective Cohort of 10 556 Brazilian Patients
Cancer Reports, Volume 9, Issue 9, September 2026.ABSTRACT Background
Prostate cancer (PCa) remains one of the most frequently diagnosed malignancies worldwide and represents a major contributor to premature mortality among men. This study aimed to estimate survival and investigate factors associated with PCa‐specific mortality among men treated within the oncology care network of a Brazilian state ...Wesley Rocha Grippa, Larissa Soares Dell'Antonio, Cristiano Soares Dell'Antônio, Luciane Bresciani Salaroli, Luís Carlos Lopes‐Júnior +4 morewiley +1 more sourceCutaneous lichen amyloidosis associated with multiple endocrine neoplasia type 2A [PDF]
, 1989 The authors describe a family with multiple endocrine neoplasia type 2A and coutaneous lichen amyloidosis , by immunocitochemical ...Lettera, A. M., D\u27Armiento, M., NUNZIATA, VINCENZO, Nunziata, V., di Giovanni, G., G. D. Giovanni, D'ARMIENTO, MARIA, Mancini, M., MANCINI, MARIO, A. Lettera +9 morecore Type B1 thymoma in multiple endocrine neoplasia type 1 (MEN-1) syndrome
, 2001 Aims and background: Multiple endocrine neoplasia (MEN) syndromes include a group of disorders characterized by the neoplastic transformation of two or more endocrine tissues. In type 1 syndrome (MEN-1), pituitary, parathyroid and pancreatic islet tumors Stefania Brozzetti, CAVALLARO, Antonino, Claudio Letizia, BROZZETTI, Stefania, Antonino Cavallaro, M. Plocco, Giorgio De Toma, DE TOMA, Giorgio, Maurizio Plocco, LETIZIA, Claudio, Virgilio Nicolanti, NICOLANTI, Virgilio +11 morecore +1 more sourceLiraglutide in Adults With Obesity: A Multicentre, Single‐Arm, Post‐Marketing Surveillance Study in Taiwan
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.In this multicentre real‐world post‐marketing surveillance (rPMS) study conducted in Taiwan, reductions in body weight and no new safety issues were observed among adults with obesity treated with liraglutide. ABSTRACT Introduction
This prospective study (NCT06283641) was the first real‐world, multicentre, post‐marketing surveillance of GLP‐1 receptor ...Shih‐Te Tu, Chiao‐Fan Chiu, Chu‐Kuang Chou, Hai‐Hua Chuang, Shu‐Wei Hu, Wen‐Ching Ko, Chun‐Ying Lee, Wen‐Yuan Lin, Yen‐Jen Sung, Thing‐Fong Tzeng, Weu Wang, Hsiang‐Fan Wu, Chun‐Yan Yeung, Bill Chen, Chet Joe Sim, Kuo‐Chin Huang +15 morewiley +1 more sourceImpact of Semaglutide, Liraglutide and Tirzepatide on Cardiometabolic Outcomes: A Comparative Narrative Review
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.The comparative pharmacology and cardiometabolic outcomes of semaglutide, liraglutide and tirzepatide, integrating evidence from major clinical trial programs and meta‐analyses. ABSTRACT Background
Cardiometabolic disorders such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD) remain major global health challenges.Hiba Bawadi, Haya Abuhijleh, Mamon Nofal, Zain Z. Zakaria, Maha Al‐Asmakh +4 morewiley +1 more sourceTargeted proteomics reveal histiocytosis‐associated neurodegeneration signatures
HemaSphere, Volume 10, Issue 9, September 2026.Abstract
Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.Egle Kvedaraite, Magda Lourda, Johannes Bastiaan Munting, Matthias Papo, Martin Jädersten, Yoko Shioda, Kenichi Sakamoto, Daniel Martín Muñoz, Panagiotis Andriopoulos, Francesco Pegoraro, Evaldas Laurencikas, Ingrid Kühnle, Joakim Wille, Leonie Naeije, Helena Olkinuora, Indranil Sinha, Daniel W. Hagey, Selma Olsson‐Åkefeldt, Fleur Cohen‐Aubart, Gustaf Österlundh, Mattias Svensson, Ahmed Idbaih, Fredrik Piehl, Kaj Blennow, Henrik Zetterberg, Tatiana Greenwood von Bahr, Désirée Gavhed, Akira Morimoto, Julien Haroche, Jan‐Inge Henter +29 morewiley +1 more sourceResidence Near Agricultural Crops at Birth and Risk of Adult Testicular Germ Cell Tumors: A French Nationwide Case–Control Study Using Historical Aerial GIS Data
International Journal of Cancer, Volume 159, Issue 5, Page 1153-1166, 1 September 2026.As the incidence of testicular germ cell tumors (TGCTs) rises, prenatal exposure to agricultural pesticides may represent an important risk factor. Here, geographic information system‐based measures of farmland proximity at birth were used as a proxy for early‐life pesticide exposure in France, a major pesticide consumer.Aurélie M. N. Danjou, Astrid Coste, Lény Grassot, Elodie Faure, Carlos Crispim‐Junior, Laure Tougne Rodet, Olivia Pérol, Rémi Béranger, Jeanne Perrin, Barbara Charbotel, Joachim Schüz, Béatrice Fervers, the TESTIS study group, Helen Boyle, Aude Fléchon, Elodie Belladame, Véronique Drouineaud, Céline Chalas, Myriam Virlouvet, Lucile Ferreux, Guillemette Perier, Pauline Peretout, Diane Rivet, Sandrine Rulle, Florence Eustache, Nathalie Sermondade, Marine Durand, Rachel Levy, Isabelle Berthaut, Jacqueline Saias‐Magnan, Catherine Metzler‐Guillemain, Carole Daoud‐Deveze, Louis Bujan, Myriam Daudin, Florence Brugnon, Valérie Bruhat, Cyril Bouche, Isabelle Kocsinski, Marius Teletin, Françoise Schmitt, Nathalie Guyomard, Aline Papaxanthos, Volcy Soula, Sandrine Giscard d’Estaing, Pascale Dehee, Delphine Yalcinkaya, Céline Bouillon, Cynthia Frapsauce, Anne Viallon, Bérengère Ducrocq, Marie‐Ange Clarotti, Ethel Szerman, Amélie Ancelle, Oxana Blagosklonov, Séverine Bey, Célia Ravel, Ségolène Veau, Agnès Letremy, Patricia Fauque, Julie Barberet, Stéphanie Lattes, Emmanuelle Thibault, Catherine Diligent, Christel Hersant, Vanessa Loup‐Cabaniols, Anna Gala, Sylvianne Hennebicq, Julien Bessonnat, Marie‐Claude Blocquaux, Brigitte Dananché, Johan Spinosi, Matthieu Dubuis, Charlotte Carretero, Etienne Durand, Bénédicte Thomas, Rémi Ratajczak +75 morewiley +1 more source