The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Double mutation for multiple endocrine neoplasia associated with congenital adrenal hyperplasia
A 39 year old female with signs of hyperandrogenism, was diagnosed with congenital adrenal hyperplasia after a cortrosyn test. Abdominal tomography showed a nodular image in the right adrenal gland, measuring 1.9 × 3.1 cm, 26 UH.
Watrusy Lima de Oliveira +7 more
doaj +1 more source
Radiological surveillance in multiple endocrine neoplasia type 1: a double-edged sword?
Context: Multiple endocrine neoplasia type 1 (MEN1) is a hereditary condition characterised by the predisposition to hyperplasia/tumours of endocrine glands.
Ruth Therese Casey +6 more
doaj +1 more source
Multiple Neuroendocrine Tumors in Stomach and Duodenum in a Multiple Endocrine Neoplasia Type 1 Patient [PDF]
A 67-year-old woman with a history of subtotal parathyroidectomy, distal pancreatectomy, and total splenectomy 23 years prior underwent surgical gastric resection for neuroendocrine tumors of the stomach and duodenum. Meticulous examination of the entire
Bohyun Kim, Han-Kwang Yang, Woo Ho Kim
doaj +1 more source
Impact of parathyroidectomy on quality of life in multiple endocrine neoplasia type 1
Background: Potential influences of parathyroidectomy (PTx) on the quality of life (QoL) in multiple endocrine neoplasia type 1-related primary hyperparathyroidism (HPT/MEN1) are unknown.
Marília D’Elboux Guimarães Brescia +9 more
doaj +1 more source
A case report of non‐syndromic colonic ganglioneuroma in a patient with juvenile polyposis
Abstract Colonic ganglioneuromas in children are rare, particularly without associated hereditary syndromes like multiple endocrine neoplasia (MEN2B), neurofibromatosis type 1(NF1), or Phosphatase and tensin homolog hamartoma tumor syndrome (PHTS). We report a 12‐year‐old male with a history of juvenile polyposis syndrome (JPS) and segmental colonic ...
Holly Coffey +2 more
wiley +1 more source
Genetic and Epigenetic Analysis in Korean Patients with Multiple Endocrine Neoplasia Type 1 [PDF]
BackgroundMultiple endocrine neoplasia type 1 (MEN1) is a familial syndrome characterized by the parathyroid, pancreas and pituitary tumors. Parathyroid tumors are the most common clinical manifestations, occurring in more than 90% of MEN1 patients ...
Yoon Jung Chung +5 more
doaj +1 more source
Nineteen cases of parathyroid carcinoma in patients with multiple endocrine neoplasia type 1 have been reported in the literature, of which 11 carry an inactivating germline mutation in the MEN1 gene.
Sara Lomelino Pinheiro +5 more
doaj +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Multiple endocrine neoplasia type 1 in children and adolescents: Clinical features and treatment outcomes [PDF]
Background: Clinical manifestations and treatment outcomes in children and adolescents with multiple endocrine neoplasia type 1 are not well characterized.
Jafar-Mohammadi, Bahram +7 more
core +1 more source

