Results 121 to 130 of about 8,287 (164)

Multiple Endocrine Neoplasia Type 1, Type 2A, and Type 2B

Primary Care - Clinics in Office Practice
Multiple endocrine neoplasia type 1 is a rare genetic neuroendocrine syndrome caused by over 1500 different germline mutations. It can cause 20 different endocrine tumors affecting primarily the parathyroid glands, gastroenteropancreatic tract, and the anterior pituitary gland.
exaly   +3 more sources

Prophylactic Thyroidectomy in Multiple Endocrine Neoplasia Type 2A

New England Journal of Medicine, 2005
Medullary thyroid carcinoma is the most common cause of death in patients with multiple endocrine neoplasia (MEN) type 2A (MEN-2A) or type 2B or familial medullary thyroid carcinoma. We sought to determine whether total thyroidectomy in asymptomatic young members of kindreds with MEN-2A who had a mutated allele of the RET proto-oncogene could prevent ...
Michael A, Skinner, Jeffrey A, Moley, William G, Dilley, Kouros, Owzar, Mary K, Debenedetti, Samuel A, Wells   +5 more
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Cervical neuroblastoma and multiple endocrine neoplasia type 2a

International Journal of Pediatric Otorhinolaryngology, 1993
The authors report the case of a female infant who was referred at the age of 18 months for a left latero-cervical mass. This child belongs to a family with a history of multiple endocrine neoplasia (MEN) type 2a (10 persons in 4 generations had medullary thyroid carcinoma and/or pheochromocytoma).
J M, Triglia, J L, Bernard, C, Scheiner
openaire   +2 more sources

Multiple Endocrine Neoplasia Type 2a and 2b

2022
Abstract Multiple endocrine neoplasia (MEN) type 2a (also referred to as type 2) is an inherited cancer syndrome in which an individual has medullary thyroid carcinoma, primary hyperparathyroidism, and/or phaeochromocytoma occurring either synchronously or metachronously.
Electron Kebebew, Douglas Wiseman, Mustapha El Lakis   +2 more
openaire   +1 more source

Primary hyperparathyroidism in multiple endocrine neoplasia type 2A

Journal of Internal Medicine, 1995
Abstract. The rarity of primary hyperparathyroidism (PHPT) in multiple endocrine neoplasia type 2A (MEN 2A) led us to study clinical findings, surgical therapy and outcome in 67 patients in order to evaluate our therapeutic strategy. The retrospective study was based on cases registered by the EUROMEN study group (nine participating centres) from 1972
F, Raue, J L, Kraimps, H, Dralle, P, Cougard, C, Proye, A, Frilling, E, Limbert, L F, Llenas, B, Niederle   +8 more
openaire   +2 more sources

[Multiple endocrine neoplasia type 2A in a family].

Orvosi hetilap, 2020
The authors present the case of a multiplex endocrine neoplasia type 2A (MEN2A). The 55-year-old woman underwent detailed examinations for abdominal complaints. Bilateral adrenal masses and thyroid nodular goiter were found. Based on metanephrine excretion and MIBG imaging, bilateral phaeochromocytomas were diagnosed. The thyroid nodules were confirmed
Ildikó, Hircsu, Annamária, Gazdag, Miklós, Bodor, Eszter, Berta, Mónika, Andrási, Zsolt, Kanyári, Ferenc, Győry, Sándor, Barna, Harjit Pal, Bhattoa, Béla, Nagy, V Endre, Nagy, Annamária, Erdei   +11 more
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Coincidence of Multiple Endocrine Neoplasia Type 2A With Acromegaly

The American Journal of the Medical Sciences, 2010
Medullary thyroid carcinoma (MTC) occurs as a part of multiple endocrine neoplasia (MEN) type 2. Acromegaly, a pituitary adenoma, occurs as a part of MEN1. Rarely, MEN2 and MEN1 coexist in a single patient simultaneously. A 40-year-old man with a history of pituitary adenomectomy for acromegaly had a surgical resection of thyroid carcinoma clinically ...
Tsunenori, Saito, Daishu, Miura, Manabu, Taguchi, Akira, Takeshita, Megumi, Miyakawa, Yasuhiro, Takeuchi   +5 more
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Subtotal Adrenalectomy for Phaeochromocytoma in Multiple Endocrine Neoplasia Type 2A

The European Journal of Surgery, 1999
To describe our surgical technique for, and results of, subtotal adrenalectomy for phaeochromocytoma in multiple endocrine neoplasia (MEN) type 2.Retrospective study.Teaching hospital, The Netherlands.6 patients (four women and 2 men, mean age 35 years, range 31-46) with MEN type 2 who presented between 1993 and 1996.Cortical sparing adrenalectomy (n ...
de Graaf, J.S., Lips, C.J.M., Rutter, J.E., van Vroonhoven, T.J.M.V.   +3 more
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Search for the Gene for Multiple Endocrine Neoplasia Type 2A

1990
Publisher Summary This chapter focuses on the mapping of the multiple endocrine neoplasia type 2A (MEN2A). MEN2A is a hereditary cancer syndrome with a unique tissue distribution. Tumors occur in multiple endocrine glands: the thyroid (specifically the C cells), the adrenals (chromaffin cells in the adrenal medulla), and occasionally the parathyroids.
K K, Kidd, N E, Simpson
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Metastatic alveolar rhabdomyosarcoma in multiple endocrine neoplasia type 2A

Pediatric Blood & Cancer, 2010
Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, accounts for 3% of childhood malignancies. Multiple Endocrine Neoplasia (MEN) type 2A is an autosomal dominant syndrome associated with near universal development of medullary thyroid carcinoma.
Ashley E, Jones, Edythe A, Albano, Mark A, Lovell, Stephen P, Hunger   +3 more
openaire   +2 more sources