Results 21 to 30 of about 8,627 (128)

Prophylactic thyroidectomy for asymptomatic 3-year-old boy with positive multiple endocrine neoplasia type 2A mutation (codon 634) [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. The multiple endocrine neoplasia type 2A (MEN 2A) syndrome, comprising medullary thyroid carcinoma (MTC), pheochromocytoma and primary hyperparathyroidism (PHPT) is most frequently caused by codon 634 activating mutations of the ...
Ješić Maja D., Tančić-Gajić Milina, Ješić Miloš M., Živaljević Vladan, Sajić Silvija, Vujović Svetlana, Damjanović Svetozar   +6 more
doaj   +1 more source

Sonographic Findings of Medullary Thyroid Carcinoma Leading to Diagnosis of Multiple Endocrine Neoplasia Type 2a during Pregnancy

American Journal of Perinatology Reports, 2011
Multiple endocrine neoplasia (MEN) type 2a (Sipple's syndrome) is characterized by medullary thyroid carcinoma and pheochromocytoma, and in a smaller percentage of cases, multiglandular parathyroid hyperplasia.
David M. Sherer, Mudar Dalloul, Ghadir Salame, Tana Shah, Eli Serur, Harry L. Zinn, Ovadia Abulafia   +6 more
doaj   +1 more source

A Familial Case of Multiple Endocrine Neoplasia 2A: From Morphology to Genetic Alterations Penetration in Three Generations of a Family

Diagnostics, 2023
This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) over a period ...
Lan Chen, Jing-Xin Zhang, Dong-Ge Liu, Hong-Gang Liu   +3 more
doaj   +1 more source

A Vietnamese MEN2A syndrome patient with C634G germline mutation of the RET proto-oncogene

Journal of Clinical and Translational Endocrinology Case Reports, 2019
Multiple endocrine neoplasia type 2A (MEN 2A) is a rare, autosomal dominant disease. It is characterized by complete penetrance of medullary thyroid carcinoma (MTC), lower prevalence of pheochromocytoma, hyperparathyroidism, and sometimes cutaneous ...
Pham Le Bich Hang, Nguyen Thi Thanh Hoa, Dao Duc Phong, Mac Thi Thom, Nguyen Dang Ton, Le Thi Thu Hien, Nong Van Hai, Nguyen Hai Ha   +7 more
doaj   +1 more source

MEN 2A WITH PRIMARY HYPERPARATHYROIDISM AND INTRATHYROIDAL PARATHYROID TISSUE: A RARE CASE REPORT

Atatürk Üniversitesi Tıp Fakültesi Cerrahi Tıp Bilimleri Dergisi, 2023
Multiple endocrine neoplasia type 2 (MEN Type 2) syndrome (Sipple syndrome) is a syndrome associated with mutations in the autosomal dominant inherited RET protooncogene.
İlyas Çapoğlu, Arzu Bilen, Sare Şipal, Zehra Altınkaynak, Sevilay Özmen, İbrahim Karabulut, Rabia Selen   +6 more
doaj  

Prominent corneal nerves in pure mucosal neuroma syndrome, a clinical phenotype distinct from multiple endocrine neoplasia type 2B

BMC Ophthalmology, 2023
Background Pure mucosal neuroma syndrome (MNS), an autosomal dominant neurocutaneous disorder, is a rare discrete subgroup in multiple endocrine neoplasia (MEN) type 2B, which present without associated endocrinopathies of MEN2B but with typical physical
L Yin, YNZ Wang, J Zhu, CY Tan, C Sun, Y Yao   +5 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Characteristics of Primary Hyperparathyroidism in Multiple Endocrine Neoplasia Type 2A

The Turkish Journal of Ear Nose and Throat
Objective: Multiple endocrine neoplasia type 2A (MEN2A) is an autosomal dominantly inherited tumour syndrome and primary hyperparathyroidism (pHPT) is one of the major components of MEN2A.
Hülya Hacışahinoğulları, Onour Chasan, Gamze Bilik Oyman, Ümmü Mutlu, İsmail Cem Sormaz, Gülşah Yenidünya Yalın, Nurdan Gül, Ayşe Kubat Üzüm, Yasemin Giles Şenyürek, Özlem Soyluk Selçukbiricik   +9 more
doaj   +1 more source

Thrombotic Microangiopathy After Spontaneous Pheochromocytoma Rupture: A Rare MEN 2A Case

Endocrinology Research and Practice, 2020
Pheochromocytoma is an adrenal medulla-derived tumor originating from the chromaffin cells that produce and secrete catecholamines. These tumors usually occur sporadically, but they may also be associated with genetic diseases, such as multiple endocrine
İlker ÇORDAN, Muhammet KOCABAŞ, Seda YILMAZ, Mustafa CAN, Melia KARAKÖSE, Hatice ÇALIŞKAN BURGUCU, Mustafa KULAKSIZOĞLU, Feridun KARAKURT   +7 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source