Results 21 to 30 of about 8,287 (164)
Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome
Clinics, 2012 OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2.
Nikoletta Lendvai +10 more
doaj +1 more source
Multiple Endocrine Neoplasia Type 2A.
Internal Medicine, 1992 A 40-year-old woman was admitted with complaints of headache, palpitation and diaphoresis. She had undergone right hemithyroidectomy 12 years previously. Histological reexamination of the operative specimen revealed a medullary thyroid carcinoma. Abdominal ultrasonography, CT scan and angiography showed bilateral adrenal tumors.
SHIMIZU, Hiroyuki +9 more
openaire +3 more sources
Journal of Medical Case Reports, 2017 Background Composite pheochromocytoma/paragangliomas are very rare tumors composed of ordinary pheochromocytoma paragangliomas associated with neurogenic tumors. Several hereditary susceptibility disorders are known to be associated with pheochromocytoma/
Boubacar Efared +6 more
doaj +1 more source
Genotype-phenotype correlation in multiple endocrine neoplasia type 2
Clinics, 2012 Multiple endocrine neoplasia type 2 is an autosomal-dominant hereditary cancer syndrome caused by missense gain-of-function mutations of the rearranged during transfection proto-oncogene, which encodes the receptor tyrosine kinase, on chromosome 10.
Friedhelm Raue, Karin Frank-Raue
doaj +1 more source
A novel mutation identified in a patient with pheochromocytoma and renal cell carcinoma [PDF]
Kosin Medical Journal, 2018 Pheochromocytomas might be sporadic or genetic. Genetic pheochromocytoma is associated with multiple endocrine neoplasia (MEN) type 2A, MEN type 2B, and von Hippel-Lindau (VHL) disease. RET mutations are identified in more than 90% of index cases of MEN2
Jae Wan Kwon +5 more
doaj +1 more source
Syncronous medullar thyroid cancer and primary hyperparathyroidism on a female within the sixth decade of life with positive family history for type 2A MEN syndrome [PDF]
Romanian Journal of Medical Practice, 2016 Medullar thyroid cancer (MTC) may be sporadic or familial, either linked with pheocromocytoma (PHEO) and primary hyperparathyrodism (PHP), as seen in type 2A MEN (Multiple Endocrine Neoplasia) syndrome, either isolated.
Ana VALEA +4 more
doaj +1 more source
Journal of the Formosan Medical Association, 2009 Multiple endocrine neoplasia type 2 (MEN 2) is an autosomal dominant cancer predisposition syndrome, and > 95% of MEN 2 patients carry rearranged during transfection (RET) protooncogene mutants.
Chin-Feng Chang +4 more
doaj +1 more source
Pancreatitis as the first manifestation of multiple endocrine neoplasia type 2A [PDF]
Arquivos Brasileiros de Endocrinologia & Metabologia, 2008 Multiple endocrine neoplasia type 2A (MEN2A) is an autosomal dominant inherited condition that predisposes to the triad of medullary thyroid cancer (MTC), pheochromocytoma (Pheo), and primary hyperparathyroidism (PHT). Nearly 100% of MEN2A are associated with germ line mutation of the RET proto-oncogene (RET), and DNA-based RET genotype analysis is now
Dora, José Miguel +4 more
openaire +5 more sources
From Childhood Migraine Headache to Pheochromocytoma
Case Reports in Endocrinology, 2014 Pheochromocytoma may have multiple clinical manifestations including paroxysmal hypertension, tachycardia, sweating, nausea, and headache (Phillips et al., 2002). Migraine has some of the manifestations seen with pheochromocytoma.
Y. M. Hazimeh +3 more
doaj +1 more source
American Journal of Perinatology Reports, 2011 Multiple endocrine neoplasia (MEN) type 2a (Sipple's syndrome) is characterized by medullary thyroid carcinoma and pheochromocytoma, and in a smaller percentage of cases, multiglandular parathyroid hyperplasia.
David M. Sherer +6 more
doaj +1 more source