Results 31 to 40 of about 5,962 (164)

[Multiple endocrine neoplasia type 2B].

Nederlands tijdschrift voor geneeskunde, 2015
BACKGROUND: Multiple endocrine neoplasia type 2b (MEN2B) is a rare syndrome characterised by the occurrence of medullary thyroid carcinoma at a young age in all patients, and phaeochromocytoma at a later age in half of the patients. Once a medullary thyroid carcinoma causes symptoms, it has usually already metastasised to the lymph nodes and curative ...
Pijnenburg-Kleizen, K.J., Santen, H.M. van, Koolen, D.A., Claahsen-van der Grinten, H.L.   +3 more
openaire   +4 more sources

RESULTADO DE DIAGNÓSTICO PRECOZ Y CIRUGÍA PROFILÁCTICA EN CARCINOMA MEDULAR HEREDITARIO DEL TIROIDES

Revista Médica Clínica Las Condes, 2018
Resumen: El cáncer medular de tiroides (CMT) es un tumor originado en las células parafoliculares tiroideas. En el 25% de los casos, los CMT son hereditarios y ocurren en el contexto de las neoplasias endocrinas múltiples tipo 2 (NEM2) A y B.
José Miguel Domínguez R-T
doaj   +1 more source

Confocal Scan Imaging and Impression Cytology of the Cornea in a Case of Multiple Endocrine Neoplasia Type-2b [PDF]

Journal of Ophthalmic & Vision Research, 2012
Mohammad-Ali Javadi, Mozhgan Rezaei Kanavi, Amir Faramarzi, Sepehr Feizi, Fereidoun Azizi, Fatemeh Javadi   +5 more
doaj   +1 more source

Positive selection for new disease mutations in the human germline: evidence from the heritable cancer syndrome multiple endocrine neoplasia type 2B. [PDF]

PLoS Genetics, 2012
Multiple endocrine neoplasia type 2B (MEN2B) is a highly aggressive thyroid cancer syndrome. Since almost all sporadic cases are caused by the same nucleotide substitution in the RET proto-oncogene, the calculated disease incidence is 100-200 times ...
Soo-Kyung Choi, Song-Ro Yoon, Peter Calabrese, Norman Arnheim   +3 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Generation of an induced pluripotent stem cell line from a patient with hereditary multiple endocrine neoplasia 2B (MEN2B) syndrome with “highest risk” RET mutation

Stem Cell Research, 2017
Multiple Endocrine Neoplasia Type 2B (MEN2B) is a cancer-predisposing syndrome that affects patients with germline RET mutations. The clinical spectrum of the syndrome includes medullary thyroid carcinoma (MTC) and pheochromocytoma.
A. Bennaceur-Griscelli, J. Hadoux, O. Féraud, P. Opolon, D. Divers, E. Gobbo, M. Schlumberger, F. Griscelli, A.G. Turhan   +8 more
doaj   +1 more source

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Isolated ileal ganglioneuromatosis in an 11-year-old boy: Case report and review of literature

Indian Journal of Pathology and Microbiology, 2016
Ganglioneuromatous proliferation in the gastrointestinal tract is a rare occurrence and is usually associated with specific syndrome complexes such as multiple endocrine neoplasia Type 2B or von Recklinghausen's disease.
Subhashis Mitra, Sanghamitra Mukherjee, Hema Chakraborty   +2 more
doaj   +1 more source