Results 61 to 70 of about 685,794 (281)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Euler and the multiplication formula for the Gamma Function
Euleriana, 2021 We show that an apparently overlooked result of Euler from \cite{E421} is essentially equivalent to the general multiplication formula for the $ $-function that was proven by Gauss in \cite{Ga28}.
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 During development, activity in the somatosensory cortex is characterized by intermittent oscillatory bursts at gamma (early gamma-oscillations, EGOs) and alpha–beta (spindle-bursts, SBs) frequencies.
Dmitrii Suchkov +3 more
doaj +1 more source
A Computer Program for Relativistic Multiple Coulomb and Nuclear Excitation
, 1998 A computer program is presented by which one may calculate the multiple electric dipole, electric quadrupole and magnetic dipole Coulomb excitation with relativistic heavy ions.
Alder +10 more
core +3 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
MathematicsThe determination of the distributions of the eigenvalues associated with matrix-variate gamma and beta random variables of either type proves to be a challenging problem. Several of the approaches utilized so far yield unwieldy representations that, for
A. M. Mathai, Serge B. Provost
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
A note on the singular Sturm-Liouville problem with infinitely many solutions
Electronic Journal of Differential Equations, 2002 We consider the Sturm-Liouville nonlinear boundary-value problem $$ displaylines{ -u''(t) = a(t)f(u(t)), quad 0 < t < 1, cr alpha u(0) - eta u'(0) =0, quad gamma u(1) + delta u'(1) = 0, } $$ where $alpha$, $eta$, $gamma$, $delta geq 0$, $alpha gamma ...
Nickolai Kosmatov
doaj
Arab Journal of Basic and Applied SciencesThis article investigates certain q-analogue of the fractional Agarwal integral operator and its application to a class of polynomials and a series of functions. By utilizing various types of q-Bessel functions, the fractional q-Agarwal integral has been
Shrideh Al-Omari
doaj +1 more source