Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Estimation of the correlation between the retention of s-triazine derivatives and some molecular descriptors [PDF]
Acta Periodica Technologica, 2011 In this study, 14 newly synthesized s-triazine derivatives were investigated by means of reversed-phase thin-layer chromatography (TLC) on C-18 stationary and two different mobile phases: acetonitrile-water and methanol-water.
Jevrić Lidija R. +5 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Transfer of flood information through multiple linear regression.
Tecnología y ciencias del agua, 2011 Maximum annual flow records (floods) are used for hydrologic dimensionality of hydraulic structures designed for protection and crossing. Logically, the longer the available series, the more reliable their probabilistic estimates or predictions.
Daniel Francisco Campos Aranda
doaj
Regression modeling of different proteins using linear and multiple analysis [PDF]
Network Biology, 2017 There are different types of regression analysis. Out of which simple regression and multiple regressions was considered in this paper. For calculation purpose we have used PLS analysis which calculates squared r values.
Shruti Jain
doaj
Analisis faktor-faktor yang mempengaruhi pendapatan petani jeruk pamelo di Kabupaten Pati
AGROMIX, 2023 The contribution of the pomelo farming revenue to the GRDP of Pati District is very low, about 0.007%. This study aims to determine the factors that affect the income of pomelo farmers in the Pati District.
Hanik Muzdalifah +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Weather based fuzzy regression models for prediction of rice yield
Journal of Agrometeorology, 2018 Fuzzy regression models for forecasting rice yield in Kanpur district were developed and compared with the weather indices-based regression model. For this, weekly (23-35 SMW) weather data (1971, 1973-2011) were utilized.
RAKHEE, ARCHANA SINGH, AMRENDER KUMAR
doaj +1 more source
Altitude and geographic coordinates to estimate monthly rainfall in the state of Mato Grosso do Sul
Bioscience Journal, 2016 Adjustment of multiple linear regression equations has allowed estimating the value of a certain climatological variable according to geographical coordinates with acceptable degree of accuracy.
Paulo Eduardo Teodoro +7 more
doaj +3 more sources
Australian Journal of Applied Linguistics, 2023 Many datasets resulting from participant ratings for word norms and also concreteness ratios are available. However, the concreteness information of infrequent words and non-words is rare.
Mohsen Dolatabadi
doaj +1 more source