Results 111 to 120 of about 146,743 (148)
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Nature Reviews Disease Primers, 2017
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
Shaji K Kumar, Pieter Sonneveld
exaly +6 more sources
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
Shaji K Kumar, Pieter Sonneveld
exaly +6 more sources
The Lancet, 2021
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
openaire +2 more sources
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
openaire +2 more sources
Ca-A Cancer Journal for Clinicians, 1966 Daniel G Miller, L F Craver, D G Miller
exaly +3 more sources
Current Treatment Options in Oncology, 2000
Multiple myeloma (MM) is an incurable plasma cell dyscrasia that remains fatal. Despite efforts over the past 3 to 4 decades, the median survival of patients with MM does not exceed 3 to 4 years. Although patients receiving combination chemotherapy have higher response rates compared with those receiving oral melphalan and prednisolone, they have no ...
N, Raje, K C, Anderson
openaire +2 more sources
Multiple myeloma (MM) is an incurable plasma cell dyscrasia that remains fatal. Despite efforts over the past 3 to 4 decades, the median survival of patients with MM does not exceed 3 to 4 years. Although patients receiving combination chemotherapy have higher response rates compared with those receiving oral melphalan and prednisolone, they have no ...
N, Raje, K C, Anderson
openaire +2 more sources
Medical Clinics of North America, 1984
Multiple myeloma is a malignant neoplasm of plasma cells involving bone and bone marrow, frequently leading to extensive skeletal destruction, bone marrow failure, renal dysfunction, and problems related to the monoclonal myeloma proteins. Vigilant supportive care and effective chemotherapy can prolong survival and improve the quality of life in most ...
openaire +2 more sources
Multiple myeloma is a malignant neoplasm of plasma cells involving bone and bone marrow, frequently leading to extensive skeletal destruction, bone marrow failure, renal dysfunction, and problems related to the monoclonal myeloma proteins. Vigilant supportive care and effective chemotherapy can prolong survival and improve the quality of life in most ...
openaire +2 more sources
Current Opinion in Oncology, 1994
The mortality associated with multiple myeloma is due to the progressive accumulation of a clonal population of plasma cells in the bone marrow. Tumor cells may also be found in the blood and other extramedullary sites, especially in the terminal stages of the disease.
M V, Seiden, K C, Anderson
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The mortality associated with multiple myeloma is due to the progressive accumulation of a clonal population of plasma cells in the bone marrow. Tumor cells may also be found in the blood and other extramedullary sites, especially in the terminal stages of the disease.
M V, Seiden, K C, Anderson
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Seminars in Oncology Nursing, 1996
To review the epidemiology, pathogenesis, clinical features, diagnosis, treatment, and nursing management of multiple myeloma.Review articles, research studies, and book chapters related to multiple myeloma.Despite insights into the immunobiology of multiple myeloma and the advances in intensive therapy and supportive care, multiple myeloma remains an ...
openaire +2 more sources
To review the epidemiology, pathogenesis, clinical features, diagnosis, treatment, and nursing management of multiple myeloma.Review articles, research studies, and book chapters related to multiple myeloma.Despite insights into the immunobiology of multiple myeloma and the advances in intensive therapy and supportive care, multiple myeloma remains an ...
openaire +2 more sources