Results 121 to 130 of about 354,322 (345)

Biologic sequelae of nuclear factor–κB blockade in multiple myeloma: therapeutic applications [PDF]

, 2002
Nicholas Mitsiades, Constantine S. Mitsiades, Vassiliki Poulaki, Dharminder Chauhan, Paul G. Richardson, Teru Hideshima, Nikhil C. Munshi, Steven P. Treon, Kenneth C. Anderson   +8 more
openalex   +1 more source

RanBALL: An Ensemble Machine Learning Framework for Accurate Subtype Identification of Pediatric B‐Cell Acute Lymphoblastic Leukemia

Advanced Intelligent Systems, EarlyView.
Here, we present RanBALL, an ensemble random projection‐based model for accurate and cost‐effective identification of B‐cell acute lymphoblastic leukemia subtypes is presented. By preserving patient‐to‐patient distance after dimension reduction by random projection and ensemble learning, RanBALL can facilitate the discovery of B‐ALL subtype‐specific ...
Lusheng Li, Hanyu Xiao, Xinchao Wu, Zhenya Tang, Joseph D. Khoury, Jieqiong Wang, Shibiao Wan   +6 more
wiley   +1 more source

Autologous peripheral blood stem cell transplantation as front-line therapy for myeloma with double-hit and triple-hit in a real-world study

Chinese Medical Journal, 2021
Guang-Zhong Yang, Guo-Rong Wang, Yan-Chen Li, Yin Wu, Wen Gao, Wen-Ming Chen, Peng Lyu   +6 more
doaj   +1 more source

Insights into organelle forming RNAs: Diversity, functions and future perspectives

Animal Models and Experimental Medicine, EarlyView.
RNA molecules play crucial roles in the formation and maintenance of cellular structures and organelles. These ‘organelle formation RNAs’ include ribosomal RNAs, paraspeckle‐forming RNAs, nuclear speckle‐forming RNAs, nucleolus‐forming RNAs, and cytoskeleton‐forming RNA.
Meng Gong, Xiangting Wang, Xiaolin Liang
wiley   +1 more source

Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation

Annals of Neurology, EarlyView.
Objective To identify clinical and radiological features of cerebral amyloid angiopathy‐related inflammation (CAA‐ri), and compare these features with those of sporadic CAA, to improve the understanding, diagnosis, and clinical care of CAA‐ri. Methods We retrospectively reviewed routine clinical data from 37 patients with CAA‐ri and 158 patients with ...
Larysa Panteleienko, Gargi Banerjee, Dermot Mallon, Kitti Thiankhaw, Rupert Oliver, Victoria Harvey, Gareth Ambler, Michael Zandi, Hans Rolf Jäger, David J. Werring   +9 more
wiley   +1 more source

Real-World Data of Light Chain (AL) Amyloidosis: Prognostic Indices and Treatment Patterns

Biomedicines
Background: Limited real-world data (RWD) may provide important information regarding diagnostic and treatment patterns in patients (pts) with AL Amyloidosis. The aim was to analyze the characteristics, treatment approach and clinical outcome of patients
Marko Mitrovic, Aleksandra Sretenovic, Natalija Kecman, Nikola Vukosavljevic, Maja Perunicic Jovanovic, Dragana Sobic Saranovic, Ruzica Maksimovic, Zoran Bukumiric, Danijela Lekovic, Arsen Ristic, Milena Todorovic Balint, Jelena Bila   +11 more
doaj   +1 more source

Daratumumab induces CD38 internalization and impairs myeloma cell adhesion

OncoImmunology, 2018
Daratumumab (Dara), a human immunoglobulin G1 kappa (IgG1κ) monoclonal anti-CD38 antibody, has been approved by the U.S. Food and Drug Administration for the treatment of relapsed multiple myeloma (MM) as a single agent as well as in combination with ...
Jayeeta Ghose, Domenico Viola, Cesar Terrazas, Enrico Caserta, Estelle Troadec, Jihane Khalife, Emine Gulsen Gunes, James Sanchez, Tinisha McDonald, Guido Marcucci, Balveen Kaur, Michael Rosenzweig, Jonathan Keats, Steven Rosen, Amrita Krishnan, Abhay R Satoskar, Craig C Hofmeister, Flavia Pichiorri   +17 more
doaj   +1 more source

Supporting people with active and advanced disease: a rapid review of the evidence [PDF]

, 2014
1.1 Background: the NCSI AAD group The National Cancer Survivorship Initiative (NCSI, 2010) was set up in response to the NHS Cancer Reform Strategy (Department of Health, 2007) as a collaboration between Macmillan Cancer Support, the Department of ...
Brooks, Joanna, Featherstone, Valerie A., King, Nigel, Topping, Annie   +3 more
core  

Profound impact of sample processing delay on gene expression of multiple myeloma plasma cells [PDF]

, 2015
Tobias Meißner, Anja Seckinger, Kari Hemminki, Uta Bertsch, Asta Foersti, Mathias Haenel, Jan Duering, Hans Salwender, Hartmut Goldschmidt, Gareth J. Morgan, Dirk Hose, Niels Weinhold   +11 more
openalex   +1 more source

Optimal timing of treatment at relapse after autologous stem cell transplantation in patients with multiple : A study of the Korean Multiple Myeloma Working Party (KMM-1909)

, 2022
Sung Hoon Jung, Chang‐Ki Min, Jae‐Hoon Lee, Yeung-Chul Moon, Soo‐Mee Bang, Dok Hyun Yoon, Ho Sup Lee, Kihyun Kım, Je‐Jung Lee   +8 more
openalex   +1 more source