Results 201 to 210 of about 5,752,243 (395)

Disc Electrophoresis Study of Serum Proteins from Patients with Multiple Myeloma and Macroglobulinemia [PDF]

, 1963
Salvador B. Zingale, Carlos A. Mattioli, HANS D. BOHNER, MARÍA P. BUENO   +3 more
openalex   +1 more source

Smoldering multiple myeloma: special considerations surrounding treatment on versus off clinical trials

Haematologica, 2014
Elisabet E Manasanch, Neha Korde, Sham Mailankody, Nishant Tageja, Manisha Bhutani, Mark Roschewski, Ola Landgren   +6 more
doaj   +1 more source

Brief Report: Two Bence Jones Proteins of Different Immunologic Types in the Same Patient with Multiple Myeloma [PDF]

, 1966
Ralph L. Engle, Ralph L. Nachman
openalex   +1 more source

Global Burden of Disease Due to High Body Mass Index and Projections to 2040: A Study Based on the Global Burden of Disease Study 2019

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background The prevalence of high body mass index (BMI) contributes to an increased risk of various diseases. This study aimed to identify global disease burden trends associated with high BMI from 1990 to 2019 and forecasts up to 2040. Methods Using data from the global burden of disease (GBD) 2019 study, we analysed the number and ratio of ...
Eun‐Ji Kim, Yoonseo Park, Sewon Park, Mihajlo Jakovljevic, Munjae Lee   +4 more
wiley   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Chromosomal Abnormalities in Multiple Myeloma [PDF]

, 1967
Kinsuk Das, B. K. Aikat
openalex   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

A Controlled Trial of Urethane Treatment in Multiple Myeloma [PDF]

, 1966
James F. Holland, Henry F. Hosley, Carol Scharlau, Paul P. Carbone, Emil Frei, Clyde O. Brindley, Thomas C. Hall, Bruce I. Shnider, G. Lennard Gold, Louis Lasagna, Albert H. Owens, Sherwood P. Miller   +11 more
openalex   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source

Multiple myeloma in Jamaica: A study of 40 cases with special reference to the incidence and laboratory diagnosis [PDF]

, 1966
H. McFarlane
openalex   +1 more source