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Identification of Extracellular Vesicle Signatures of Daratumumab Treated Multiple Myeloma. [PDF]
Brennan K +5 more
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The Lancet, 2021
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
exaly +5 more sources
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
exaly +5 more sources
British Journal of Hospital Medicine, 2017
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
S J, Chavda, K, Yong
exaly +7 more sources
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
S J, Chavda, K, Yong
exaly +7 more sources
Diagnosis and Management of Multiple Myeloma: A Review.
Journal of the American Medical Association (JAMA), 2022Importance Multiple myeloma is a hematologic malignancy characterized by presence of abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth causing destructive bone lesions, kidney injury, anemia, and hypercalcemia ...
A. Cowan +8 more
semanticscholar +1 more source
Hematology/Oncology Clinics of North America, 2014
Autologous stem cell transplant (ASCT) remains an integral part of the treatment strategy for many myeloma patients. The role of allogeneic stem cell transplant continues to be defined. There is increasing evidence that posttransplant maintenance therapy can significantly improve outcomes.
Sarah A, Holstein +2 more
+7 more sources
Autologous stem cell transplant (ASCT) remains an integral part of the treatment strategy for many myeloma patients. The role of allogeneic stem cell transplant continues to be defined. There is increasing evidence that posttransplant maintenance therapy can significantly improve outcomes.
Sarah A, Holstein +2 more
+7 more sources
The Lancet Haematology, 2022
BACKGROUND Multiple myeloma accounted for 176 404 (14%) of 1 278 362 the incidence cases leukaemia, lymphoma, and multiple myeloma in 2020. Identifying its geographical distribution, risk factors, and epidemiological trends could help identify high-risk ...
Junjie Huang +9 more
semanticscholar +1 more source
BACKGROUND Multiple myeloma accounted for 176 404 (14%) of 1 278 362 the incidence cases leukaemia, lymphoma, and multiple myeloma in 2020. Identifying its geographical distribution, risk factors, and epidemiological trends could help identify high-risk ...
Junjie Huang +9 more
semanticscholar +1 more source
NCCN Guidelines® Insights: Multiple Myeloma, Version 3.2022.
The Journal of the National Comprehensive Cancer Network, 2022The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis, initial workup, treatment, follow-up, and supportive care for patients with various plasma cell neoplasms, including multiple myeloma.
Natalie S. Callander +28 more
semanticscholar +1 more source

