Results 301 to 310 of about 5,628,828 (349)
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The Lancet, 2021
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
openaire +3 more sources
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in which initiating genetic abnormalities, such as hyperdiploidy and translocations involving the ...
Niels W C J, van de Donk +2 more
openaire +3 more sources
BMJ, 2012
Multiple myeloma (MM) is a clonal accumulation of malignant plasma cells (PCs) that typically produce a monoclonal immunoglobulin (Ig) (or fragment thereof), termed M-protein, detectable in the serum or urine. Despite recent advances in its treatment (median overall survival is now 5–7 years, compared to 2–3 years for patients diagnosed 10 or more ...
Danny C, Hsu +2 more
+8 more sources
Multiple myeloma (MM) is a clonal accumulation of malignant plasma cells (PCs) that typically produce a monoclonal immunoglobulin (Ig) (or fragment thereof), termed M-protein, detectable in the serum or urine. Despite recent advances in its treatment (median overall survival is now 5–7 years, compared to 2–3 years for patients diagnosed 10 or more ...
Danny C, Hsu +2 more
+8 more sources
Diagnosis and Management of Multiple Myeloma: A Review.
Journal of the American Medical Association (JAMA), 2022Importance Multiple myeloma is a hematologic malignancy characterized by presence of abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth causing destructive bone lesions, kidney injury, anemia, and hypercalcemia ...
A. Cowan +8 more
semanticscholar +1 more source
NCCN Guidelines® Insights: Multiple Myeloma, Version 3.2022.
The Journal of the National Comprehensive Cancer Network, 2022The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis, initial workup, treatment, follow-up, and supportive care for patients with various plasma cell neoplasms, including multiple myeloma.
Natalie S. Callander +28 more
semanticscholar +1 more source
Nature Reviews Disease Primers, 2017
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
Kumar S. K. +7 more
openaire +5 more sources
Multiple myeloma is a malignancy of terminally differentiated plasma cells, and patients typically present with bone marrow infiltration of clonal plasma cells and monoclonal protein in the serum and/or urine. The diagnosis of multiple myeloma is made when clear end-organ damage attributable to the plasma cell proliferative disorder or when findings ...
Kumar S. K. +7 more
openaire +5 more sources
Hematology/Oncology Clinics of North America, 2014
Autologous stem cell transplant (ASCT) remains an integral part of the treatment strategy for many myeloma patients. The role of allogeneic stem cell transplant continues to be defined. There is increasing evidence that posttransplant maintenance therapy can significantly improve outcomes.
Sarah A, Holstein +2 more
+7 more sources
Autologous stem cell transplant (ASCT) remains an integral part of the treatment strategy for many myeloma patients. The role of allogeneic stem cell transplant continues to be defined. There is increasing evidence that posttransplant maintenance therapy can significantly improve outcomes.
Sarah A, Holstein +2 more
+7 more sources
Oral Surgery, Oral Medicine, Oral Pathology, 1974
Abstract A case is presented in which examination of a routine Panorex film led to the detection of multiple myeloma.
A.H. Shawkat, James D. Phillips
openaire +4 more sources
Abstract A case is presented in which examination of a routine Panorex film led to the detection of multiple myeloma.
A.H. Shawkat, James D. Phillips
openaire +4 more sources
Current Treatment Options in Oncology, 2000
Multiple myeloma (MM) is an incurable plasma cell dyscrasia that remains fatal. Despite efforts over the past 3 to 4 decades, the median survival of patients with MM does not exceed 3 to 4 years. Although patients receiving combination chemotherapy have higher response rates compared with those receiving oral melphalan and prednisolone, they have no ...
Kenneth C. Anderson, Noopur Raje
openaire +3 more sources
Multiple myeloma (MM) is an incurable plasma cell dyscrasia that remains fatal. Despite efforts over the past 3 to 4 decades, the median survival of patients with MM does not exceed 3 to 4 years. Although patients receiving combination chemotherapy have higher response rates compared with those receiving oral melphalan and prednisolone, they have no ...
Kenneth C. Anderson, Noopur Raje
openaire +3 more sources