Results 111 to 120 of about 9,918,984 (250)
Analysis of Grain Supply Chain Performance Based on Relative Impact of Channel Coordinator's Objectives on Firm Level Objectives [PDF]
A fuzzy multi-objective programming model is used to analyze the optimal decisions in a multi-objective grain supply chain in which the firm-level firm goals are conflicting with the channel coordinator's goals.
Mazzocco, Michael A. +1 more
core
Scientific ReportsMulti-objective and multi-stage decision-making problems require balancing multiple objectives at each stage and making optimal decision in multi-dimensional control variables, where the commonly used intelligent optimization algorithms suffer from low ...
Zhihao Liang +3 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Multiple Objective Programming Support.
This paper gives a brief introduction into multiple objective programming support. We will overview basic concepts, formulations, and principles of solving multiple programming problems.To solve those problems requires the the intervention of a decision ...
P. Korhonen
core
, 2010 Bilevel-programming techniques are developed to handle decentralized problems with two-level decision makers, which are leaders and followers, who may have more than one objective to achieve.
Guangquan Zhang (6938171) +3 more
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Idea by multiple objective programming
, 2020 [[abstract]]The purpose of this paper is to propose a multiple objective programming (MOP) for imprecise data envelopment analysis (IDEA). The proposed model has four advantages: (1) Unlike both Despotis and Smirlis's and Cooper et al.'s methods, the ...
余菁蓉, Yu, JR
core