Results 151 to 160 of about 9,918,984 (250)

Resilience enhancement-oriented traffic police service district division and patrol route planning. [PDF]

PLoS One
Ju Y, Chen J, Ou M, Liu X, Zhu S, Chen T, Chen L.   +6 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

A Quantum Annealing Approach for Solving Optimal Feature Selection and Next Release Problems. [PDF]

Entropy (Basel)
Zhang Y, Wang S, Yang W.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Real-world deep brain stimulation programming practices for Parkinson's disease in India: variability, technology adoption, and emerging trends from a multicentre clinician survey across India. [PDF]

Front Neurol
Pal PK, Rajan R, Krishnan Nair S, Yadav R, Anand M, Balakrishnan S, Baldia M, Banarjee AD, Borgohain R, Ganguly J, Ginjupally DR, Holla VV, Hosurkar G, Kamble N, Kandadai RM, Kayal A, Kohat AK, Kumar H, Mahale RR, Matur V, Prasad S, Shiva Kumar R, Sheikh A, Shetty K, Singh S, Venkatachalam A, Shankar V, Vysakh KV, Yareeda S.   +28 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Optimizing university course timetabling for metaverse integration: a human-centered decision model in medical education. [PDF]

BMC Med Educ
Damar S, Koksalmis GH.
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Introducing GalaxyR: an easy-to-use R implementation of the Galaxy API. [PDF]

BMC Bioinformatics
Frey J, Schindler Z, Ali M, Braun-Wimmer J, Gerberding K, Kröner K, Larysch E, Lusk D, Vanja-Jehle J, Wardius Y, Weidenfeller M, Kattenborn T, Seifert T.   +12 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source