Results 171 to 180 of about 9,918,984 (250)

Objective Hair Shaft Diameter Measurement From Trichoscopic Images Using Intensity Profile Analysis. [PDF]

Cureus
Martínez-Ortega JI, Rosas-Lezama FI.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Prioritising place-based strategies for sexually transmitted and blood-borne infection prevention: protocol for the <i>Zingatia Maskan</i> interactive, convergent mixed-methods study in Nairobi, Kenya. [PDF]

BMJ Open
McClarty LM, Gitau AK, Herpai N, Kimani J, Kinyua AK, Kiplagat A, Micheni M, Muriuki F, Oside D, Wanjiru RK, Isac S, Lazarus L, Lorway RR, McKinnon LR, Mishra S, Shaw SY, Bhattacharjee P, Becker ML, Zingatia Maskan Study Team.   +18 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Organizational Implementation Capacity of Vocational Rehabilitation During Secondary Transition for Individuals with Intellectual Disabilities: A Preliminary Study in Al-Kharj, Saudi Arabia. [PDF]

J Intell
Almalky HA, Alwadei AM.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sustainable-resilient and climate-responsive e-waste supply chain network design under uncertainty using four-valued refined neutrosophic optimization. [PDF]

Sci Rep
Saeed A, Jian M, Imran M, Dong ZS, Freen G.   +4 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

The Influence of Different Types of Trust, Perceived Objectivity, and Perceived Risk on the Preferred Involvement of AI for Subjective and Objective Tasks. [PDF]

Risk Anal
Michel F, Siegrist M.
europepmc   +1 more source