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Multiple organ dysfunction syndrome: what do we know about pain management? A narrative review
Dmytro Dmytrіiev +3 more
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From mechanism to phenotype: What fits in a basket trial
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Kette D. Valente
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Multiple Organ Dysfunction Syndrome
2023Abstract Multiple organ dysfunction syndrome (MODS) is a spectrum of physiologic maladaptation in separate organs that leads to significant morbidity and mortality in intensive care unit patients. This dysfunction is rooted in the dysregulated immune response and imbalance of the pro-inflammatory and anti-inflammatory responses to a ...
Peter Shehata, Wael Ali Sakr Esa
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Multiple organ dysfunction syndrome
InflammoPharmacology, 2003Multiple organ dysfunction syndrome, including acute respiratory distress syndrome (ARDS) and renal failure, is described, its clinical features outlined, its origins in tissue oxidative stress following severe infections, surgical trauma, ionizing radiation, high-dosage drugs and chemicals, severe hemorrhage, etc., are defined, and its prevention and ...
A L, Parke, P T, Liu, D V, Parke
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Multiple Organ Dysfunction Syndrome
Journal of Intensive Care Medicine, 2019Multiple organ dysfunction syndrome (MODS) is one of the most common syndromes of critical illness and the leading cause of mortality among critically ill patients. Multiple organ dysfunction syndrome is the clinical consequence of a dysregulated inflammatory response, triggered by clinically diverse factors with the main pillar of management being ...
Nicholas M. Gourd, Nikitas Nikitas
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Multiple Organ Dysfunction Syndrome
2014Multiple organ dysfunction syndrome (MODS) occurs after a life-threatening primary insult, including severe infection, hypoxic-ischemic injury, or other serious injuries. It represents a continuum of physiological abnormalities rather than a distinct state (present or absent).
François Proulx +3 more
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Multiple Organ Dysfunction Syndrome
DeckerMed Surgery, 2015The concept of and approach to multiple organ dysfunction syndrome (MODS), also known as progressive systems failure, multiple organ failure, and multiple system organ failure, have evolved over the last decade. Characterized by progressive but potentially reversible tissue damage and dysfunction of two or more organ systems that arise after a ...
Robert A.N. Goggs, Daniel Huw Lewis
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Multiple Organ Dysfunction Syndrome After Multiple Trauma
Orthopaedic Nursing, 2005Multiple organ dysfunction syndrome (MODS) is a serious, often fatal, sequel to multiple trauma. Prolonged shock states, severe sepsis, acute pancreatitis, acute renal failure, severe burns, ischemic conditions, and acute respiratory distress syndrome have been implicated in the development of MODS.
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Multiple Organ Dysfunction Syndrome
Current Problems in Pediatric and Adolescent Health Care, 2013Initially known as multiple system organ failure, the term multiple organ dysfunction syndrome (MODS) was first described in the 1960s in adults with bleeding, respiratory failure, and sepsis. It is defined as "the development of potentially reversible physiologic derangement involving two or more organ systems not involved in the disorder that ...
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