Results 41 to 50 of about 322,913 (349)

Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]

, 2020
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul, De Herdt, Veerle, Garrez, Ieme, Hemelsoet, Dimitri, Laureys, Guy, Raedt, Robrecht, Vonck, Kristl   +6 more
core   +2 more sources

Critical care hepatology: definitions, incidence, prognosis and role of liver failure in critically ill patients

Critical Care, 2022
Organ dysfunction or overt failure is a commonplace event in the critically ill affecting up to 70% of patients during their stay in the ICU. The outcome depends on the resolution of impaired organ function, while a domino-like deterioration of organs ...
Aritz Perez Ruiz de Garibay, Andreas Kortgen, Julia Leonhardt, Alexander Zipprich, Michael Bauer   +4 more
doaj   +1 more source

Impact of mannitol on mortality in patients with non-traumatic intracerebral haemorrhage and acute kidney injury: a retrospective study

Scientific Reports
Mannitol is widely used for treating brain edema caused by various diseases, but it has been reported to cause acute kidney injury. However, the prognosis for patients with non-traumatic intracerebral hemorrhage who also have acute kidney injury and ...
Weixiao Chen, Qingzhou Chen, Yuli Wang, Qilin Yang, Weiyan Chen, Lili Tao, Jiezhao Zheng, Deliang Wen, Zhenhui Zhang   +8 more
doaj   +1 more source

Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important Innate Immune Response Genes [PDF]

, 2015
Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma.
Bronkhorst, M.W.G.A. (Maarten), Lieshout, E.M.M. (Esther) van, Patka, P. (Peter)   +2 more
core   +2 more sources

Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies [PDF]

Pediatric Critical Care Medicine, 2017
Objective: To describe the state of the science, identify knowledge gaps, and offer potential future research questions regarding promising therapies for children with multiple organ dysfunction syndrome presented during the Eunice Kennedy Shriver National Institute of Child Health and Human Development Workshop on Pediatric ...
Allan, Doctor, Jerry, Zimmerman, Michael, Agus, Surender, Rajasekaran, Juliane, Bubeck Wardenburg, James, Fortenberry, Anne, Zajicek, Emma, Mairson, Katri, Typpo   +8 more
openaire   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Trained Immunity Exacerbates Inflammatory Arthritis Progression via Promoting Synovial Fibroblast Ferroptotic Resistance

Advanced Science
Trained immunity induced by β‐glucan insult drives the functional reprogramming of macrophages to the hyperinflammatory status, contributing to developing or maintaining inflammatory diseases.
Haibo Su, Baoying Zhang, Qiudi Deng, Jiaxin Huang, Jinyu Feng, Yuan Fu, Yuejun Huang, Weikun Deng, YingJun Su, Huisheng Liu, Ning‐yi Shao, Zhenhui Zhang, Jianwei Dai   +12 more
doaj   +1 more source

How to deal with an open abdomen? [PDF]

, 2015
Appropriate open abdomen treatment is one of the key elements in the management of patients who require decompressive laparotomy or in whom the abdomen is left open prophylactically.
Bjorck, Martin, De Waele, Jan, Kaplan, Mark, Sibaja, Pablo, Sugrue, Michael   +4 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple organ dysfunction syndrome: a narrative review [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2001
To review multiple organ dysfunction syndrome with respect to: 1) clinical measurement systems; 2) molecular mechanisms; and 3) therapeutic directions based upon molecular mechanisms.The Medline, Cochrane, and Best Evidence databases (1996 to 2000), conference proceedings, bibliographies of review articles were searched for relevant articles. Key index
D, Johnson, I, Mayers
openaire   +2 more sources