Results 1 to 10 of about 747,976 (204)

Neonatal multiple organ failure after perinatal asphyxia

Anales de Pediatría (English Edition), 2022
Perinatal asphyxia is an event with far-reaching consequences that can lead not only to the development of neonatal encephalopathy, but also to multiple organ failure (MOF).
Isabel Iribarren, Enrique Hilario, Antonia Álvarez, Daniel Alonso-Alconada   +3 more
doaj   +2 more sources

DNA-PKcs promotes sepsis-induced multiple organ failure by triggering mitochondrial dysfunction

Journal of Advanced Research, 2022
Introduction: Multiple organ failure is the commonest cause of death in septic patients. Objectives: This study was undertaken in an attempt to elucidate the functional importance of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) on ...
Rongjun Zou, Jun Tao, Junxiong Qiu, Huimin Lu, Jianhua Wu, Hang Zhu, Ruibing Li, David Mui, Sam Toan, Xing Chang, Hao Zhou, Xiaoping Fan   +11 more
doaj   +2 more sources

The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience

Critical Care, 2020
Background Sepsis remains a common condition with high mortality when multiple organ failure develops. The evidence for therapeutic plasma exchange (TPE) in this setting is promising but inconclusive.
Philip D. Keith, Adam H. Wells, Jeremy Hodges, Stephen H. Fast, Amber Adams, L. Keith Scott   +5 more
doaj   +2 more sources

Case report: Multiple organ failure caused by Japanese spotted fever [PDF]

Heliyon
A 71-year-old male had disseminated multiple organ dysfunction syndrome (MODS). Following treatment with cefotaxime and piperacillin-tazobactam, his symptoms have worsened instead.
Pei Zhou, Yinhui Zhu, Qian Cai, Zhe Li, Yuyang Yu, Yingqun Zhu, Lan Guan   +6 more
doaj   +2 more sources

Multiple Organ Failure [PDF]

Definitions, 2020
openaire   +2 more sources

Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials

Critical Care, 2022
Background Thrombotic microangiopathy-induced thrombocytopenia-associated multiple organ failure and hyperinflammatory macrophage activation syndrome are important causes of late pediatric sepsis mortality that are often missed or have delayed diagnosis.
Yidi Qin, Kate F. Kernan, Zhenjiang Fan, Hyun-Jung Park, Soyeon Kim, Scott W. Canna, John A. Kellum, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley, Tim Cornell, Rick E. Harrison, Athena F. Zuppa, Russell Banks, Ron W. Reeder, Richard Holubkov, Daniel A. Notterman, J. Michael Dean, Joseph A. Carcillo   +24 more
doaj   +1 more source

Procalcitonin Level and Organ Dysfunction in Children with Sepsis: A Prospective Observational Study

Journal of Nobel Medical College, 2022
Background: Procalcitonin is produced in response to endotoxin or mediators released in response to bacterial infections and are reported to be sensitive predictor of sepsis and multiple organ failure.
Sandip Kumar Singh, Vikash Kumar Sah, Parag Shankarrao Dekate   +2 more
doaj   +1 more source

Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications

Inflammation, 2020
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19).
M. Iwasaki, J. Saito, Hailin Zhao, A. Sakamoto, K. Hirota, D. Ma   +5 more
semanticscholar   +1 more source

Multiple Organ Failure

Clinics in Chest Medicine, 1990
Diagnostic criteria for individual organ system failure are imprecise, a factor that adds a considerable amount of ambiguity to this area of clinical research. Nonetheless, multiple organ failure is a common sequela of ARDS and other catastrophic medical and surgical illnesses that continues to limit patient survival.
P M, Dorinsky, J E, Gadek
  +6 more sources

Angiotensin-converting enzyme 2 (ACE2): COVID 19 gate way to multiple organ failure syndromes

Respiratory Physiology & Neurobiology, 2020
Background Globally, the current medical emergency for novel coronavirus 2019 (COVID-19) leads to respiratory distress syndrome and death. Purpose This review highlighted the effect of COVID-19 on systemic multiple organ failure syndromes. This review is
Sundareswaran Loganathan, M. Kuppusamy, Wankupar Wankhar, K. Gurugubelli, Vidyashree Mahadevappa, Lhakit Lepcha, A. Choudhary   +6 more
semanticscholar   +1 more source