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Postinjury multiple organ failure
Injury, 2009Postinjury multiple organ failure (MOF) became prevalent as the improvements in critical care during the 1970s made it possible to keep trauma patients alive with single organ injury. Enormous efforts invested in laboratory and clinical research made it possible to better understand the epidemiology and pathophysiology of the syndrome.
Dewar, David +3 more
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Multiple-Organ-Failure Syndrome
Archives of Surgery, 1986INCIDENCE AND PROBLEMS OF MULTIPLE-ORGAN-FAILURE SYNDROMES The panelists for the discussion were C. James Carrico, MD, from Seattle; Jonathan Meakins, MD, DSc, FRCSC, FACS, from Montreal; Donald Fry, MD, from Cleveland; and Ronald V. Maier, MD, from Seattle. Dr Carrico: Multiple-organ-failure (MOF) syndrome is a process that occurs following 7% to 22%
C J, Carrico +4 more
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Multiple organ failure syndrome
Critical Care Nurse, 1994Although many new areas of research are directed at the regulatory aspects of the metabolic response, the prognosis of MOF remains poor. Critical care nurses, challenged to provide a supportive environment during this life-threatening syndrome, must understand its onset, clinical patterns, and prolonged support required by patients. Such knowledge will
E, Reilly, C B, Yucha
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Archives of Surgery, 1985
As multiple-organ failure (MOF) has been generally associated with sepsis, the importance of bacterial sepsis was evaluated retrospectively in 55 trauma and 37 intra-abdominal-sepsis patients with MOF. The severity of MOF was graded, and an analysis was made of day of onset, incidence, severity, sequence, and mortality of organ failures.
R J, Goris +3 more
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As multiple-organ failure (MOF) has been generally associated with sepsis, the importance of bacterial sepsis was evaluated retrospectively in 55 trauma and 37 intra-abdominal-sepsis patients with MOF. The severity of MOF was graded, and an analysis was made of day of onset, incidence, severity, sequence, and mortality of organ failures.
R J, Goris +3 more
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Multiple Organ Failure Syndrome
Perspectives in Vascular Surgery and Endovascular Therapy, 1990Tissue injury, whether from infection, blood or volume loss, trauma, or inflammation such as pancreatitis, induces local and systemic responses. The systemic responses include shock, reperfusion, systemic inflammation (hypermetabolism) with primary organ dysfunction, and secondary organ dysfunction that either becomes progressive and leads to death or ...
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Postoperative Multiple Organ Failure
Critical Care Clinics, 1987Cellular damage is the pathophysiologic basis for the postoperative multiple organ failure syndrome. This damage may be caused by pre- and intraoperative shock. Postoperative organ failure is manifested when cellular repair does not occur. Three factors may contribute to this progression to multiple organ failure: inadequate resuscitation, malnutrition,
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Surgical Clinics of North America, 1988
Multiple system organ failure represents the final common pathway to a fatal outcome in severely infected patients. Despite the development of extensive support technology, the mortality rate in this group of patients remains high: in excess of 50 per cent. This rate underscores the need for newer treatment modalities.
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Multiple system organ failure represents the final common pathway to a fatal outcome in severely infected patients. Despite the development of extensive support technology, the mortality rate in this group of patients remains high: in excess of 50 per cent. This rate underscores the need for newer treatment modalities.
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Intensive Care Medicine, 1992
Progressive failure of several organ systems as the final pathway in critical surgical illness was first described by Skillman et al. in 1969 [1] and Tilney et al. in 1973 [2]. It remained for Baue in 1975 to define the syndrome [3]. Fry [4] correlated the syndrome to uncontrolled infection.
Sheng Zhi-yong +2 more
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Progressive failure of several organ systems as the final pathway in critical surgical illness was first described by Skillman et al. in 1969 [1] and Tilney et al. in 1973 [2]. It remained for Baue in 1975 to define the syndrome [3]. Fry [4] correlated the syndrome to uncontrolled infection.
Sheng Zhi-yong +2 more
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Lancet (London, England), 1977
Forty-two postoperative patients, each with demonstrable failure of two or more vital organ systems, have been studied as they define a syndrome of multiple organ failure. They typify the emerging clinical entity of patients kept alive solely by reason of specific mechanical and pharmacologic support. Trauma initiated hospitalization in 40 per cent and
B, Eiseman, R, Beart, L, Norton
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Forty-two postoperative patients, each with demonstrable failure of two or more vital organ systems, have been studied as they define a syndrome of multiple organ failure. They typify the emerging clinical entity of patients kept alive solely by reason of specific mechanical and pharmacologic support. Trauma initiated hospitalization in 40 per cent and
B, Eiseman, R, Beart, L, Norton
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Thrombocytopenia-Associated Multiple Organ Failure
Critical Care Clinics, 2020Thrombocytopenia-associated multiple organ failure is a clinical phenotype encompassing a spectrum of syndromes associated with disseminated microvascular thromboses. Autopsies performed in patients that died with thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, or disseminated intravascular coagulation reveal specific findings that can ...
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