Multiple osteochondromas: mutation update and description of the multiple osteochondromas mutation database (MOdb) [PDF]
Human Mutation, 2009 Multiple osteochondromas (MO) is an autosomal dominant skeletal disease characterized by the formation of multiple cartilage-capped bone tumors growing outward from the metaphyses of long tubular bones. MO is genetically heterogeneous, and is associated with mutations in Exostosin-1 (EXT1) or Exostosin-2 (EXT2), both tumor-suppressor genes of the EXT ...
Jennes, Ivy +9 more
openaire +5 more sources
EXT1 and EXT2 Variants in 22 Chinese Families With Multiple Osteochondromas: Seven New Variants and Potentiation of Preimplantation Genetic Testing and Prenatal Diagnosis [PDF]
Frontiers in Genetics, 2020 Multiple osteochondromas (MO), the most common type of benign bone tumor, is an autosomal dominant skeletal disorder characterized by multiple cartilage-capped bony protuberances.
Ye Wang +13 more
doaj +2 more sources
Osteochondroma Arising from Dorsal Pedicle Causing Compressive Myelopathy [PDF]
Journal of Orthopaedic Case ReportsIntroduction: Osteochondromas are benign bony neoplasms typically located in long bones, though they may occasionally occur in the posterior elements of the spine.
Mantu Jain +5 more
doaj +2 more sources
Structural Features of Heparan Sulfate from Multiple Osteochondromas and Chondrosarcomas [PDF]
Molecules, 2018 Multiple osteochondromas (MO) is a hereditary disorder associated with benign cartilaginous tumors, known to be characterized by absence or highly reduced amount of heparan sulfate (HS) in the extracellular matrix of growth plate cartilage, which alters ...
Noemi Veraldi +9 more
doaj +2 more sources
Multiple osteochondromas of the antlers and cranium in a free-ranging white-tailed deer (Odocoileus virginianus). [PDF]
PLoS ONE, 2017 This paper reports a case of multiple osteochondromas affecting the antlers and the left zygomatic bone of a free-ranging adult white-tailed buck (Odocoileus virginianus) from Georgia, USA.
Uwe Kierdorf +4 more
doaj +2 more sources
Arthroscopic Anterior Cruciate Ligament Reconstruction in a 17-Year-Old Female Athlete with Multiple Hereditary Exostoses Using a Peroneus Longus Autograft: A Rare Case Report [PDF]
Journal of Orthopaedic Case ReportsIntroduction: Hereditary multiple exostoses, also known as multiple osteochondromas, is a rare genetic disorder marked by the formation of osteocartilaginous outgrowths predominantly near the metaphysis of long bones.
Sanjay Singh Chauhan +2 more
doaj +2 more sources
The Rizzoli Multiple Osteochondromas Classification revised: describing the phenotype to improve clinical practice. [PDF]
Am J Med Genet A, 2021 Mordenti M +12 more
europepmc +2 more sources
Case Reports in Orthopedic Research, 2022 Vascular complications of osteochondromas of the humerus are extremely rare. Only 9 cases with pseudoaneurysms of the brachial artery complicating osteochondromas of the humerus were reported in 7 English articles.
Ashraf A. Khanfour +2 more
doaj +1 more source
An unusual diagnosis for an usual test
Italian Journal of Pediatrics, 2020 Background Hereditary multiple osteochondromas (HMO) is a genetic condition characterized by the presence of multiple osteochondromas, usually at the lateral side of the most active growth plate of a long bone.
Andrea Trombetta +4 more
doaj +1 more source
In Situ Hybridization of Feline Leukemia Virus in a Case of Osteochondromatosis
Veterinary Sciences, 2022 Osteochondromatosis, also known as multiple cartilaginous exostosis, polyostotic osteochondroma, and multiple osteochondromas, comprises one-fifth of all primary bone tumors in cats, with no breed or sex predisposition or hereditary pattern.
Anna Szilasi +4 more
doaj +1 more source