Results 91 to 100 of about 5,623,927 (307)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Interventions for promoting smoking cessation during pregnancy. [PDF]

, 2009
BACKGROUND: Tobacco smoking in pregnancy remains one of the few preventable factors associated with complications in pregnancy, low birthweight, preterm birth and has serious long-term health implications for women and babies.
Oliver, Sandy, Watson, Lyndsey, Sandy Oliver, Chamberlain, Catherine, Lyndsey Watson, Judith Lumley, Lumley, Judith, Catherine Chamberlain, Laura Oakley, Dowswell, Therese, Therese Dowswell, Oakley, Laura   +11 more
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Promoting positive adolescent sexual health & preventing teenage pregnancy - a review of recent effectiveness research

, 2004
This review was commissioned by the Crisis Pregnancy Agency to inform their work in the area of prevention of crisis pregnancy. The review commences with a brief description of the current epidemiological data on teenage pregnancy and adolescent ...
Fullerton, Deirdre
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Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Is a Blanket Elective Single Embryo Transfer Policy Defensible?

Rambam Maimonides Medical Journal, 2017
For the purpose of reducing maternal and neonatal morbidity, elective single transfer (eSET) in in vitro fertilization (IVF) was first proposed in 1999. The purpose of this review is to summarize recent oral debate between a proponent and an opponent of ...
Eli Y. Adashi, Norbert Gleicher
doaj   +1 more source

Pregnancy and multiple sclerosis (the PRIMSstudy): clinical predictors of post-partum relapse

, 2004
The in ̄uence of pregnancy in multiple sclerosis has been a matter of controversy for a long time. The Pregnancy in Multiple Sclerosis (PRIMS) study was the ®rst large prospective study which aimed to assess the possible in ̄uence of pregnancy and ...
Patricia Cortinovis Tourniaire, Michael Hutchinson, Thibault Moreau, Patrice Adeleine, Christian Confavreux, the Pregnancy In Multiple Sclerosis Group, Martine Hours, Sandra Vukusic, THOMAS, Astrid Maria   +8 more
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Smoking cessation during pregnancy: the influence of partners, family and friends on quitters and non-quitters [PDF]

, 2010
This research compared pregnant quitters’ and non-quitters’ accounts of how partners, family and friends influenced their smoking cessation attempts.
P. Koshy, L. Bauld, Koshy, P., Mackenzie, M., Tappin, D., Bauld, L., D. Tappin, Tappin, David, Mackenzie, Mhairi, Bauld, Linda, M. Mackenzie, Koshi, Preethi   +11 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

A study of sexual health issues attitudes and behaviours: The view of early school leavers [PDF]

, 2004
A core objective of this study was the systematic investigation of the sexual attitudes, beliefs and behaviours of early school leavers. The study also aimed to explore the process and mechanisms whereby young people construct, experience and define ...
Byrne, Tina, Mayock, Paula
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