Results 111 to 120 of about 491,901 (263)

Comparing Outcomes and Risks of Multiple Gestations: Assisted versus Spontaneous Conceptions

International Journal of Women's Health
Rwan K Alarfaj,1,2 Aseel Alwahhabi,1,2 Renad Alshalan,1,2 Yara Alabdulkareem,1,2 Deamah Alabdulkareem,1,2 Feras Alkharouf2,3 1College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 2King Abdullah International ...
Alarfaj RK, Alwahhabi A, Alshalan R, Alabdulkareem Y, Alabdulkareem D, Alkharouf F   +5 more
doaj  

Effect of double embryo transfer derived from autologous frozen oocytes on multiple pregnancy rates and presentation of success rates stratified by age at retrieval [PDF]

J Turk Ger Gynecol Assoc, 2021
Badeghiesh A, Konci R, Aldhaheri S, Son WY, Dahan MH.   +4 more
europepmc   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Increased risk of multiple pregnancy complications following large-scale power outages during Hurricane Sandy in New York State. [PDF]

Sci Total Environ, 2021
Xiao J, Zhang W, Huang M, Lu Y, Lawrence WR, Lin Z, Primeau M, Dong G, Liu T, Tan W, Ma W, Meng X, Lin S.   +12 more
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Perinatal outcomes of monochorionic monoamniotic twin pregnancies

Journal of Perinatal Medicine
To describe the risk of early and late fetal loss of a cohort of monochorionic monoamniotic (MCMA) twin pregnancies; secondary objectives are to describe perinatal outcomes of these pregnancies and to identify which obstetric variables mostly influence ...
Roero Sofia, Arduino Silvana, Ingala Agata, Peila Chiara, Bossotti Carlotta, Ferrando Isabella, Folino Gallo Miriam, Greco Maria Francesca, Aiello Alessandra, Coscia Alessandra, Revelli Alberto   +10 more
doaj   +1 more source

Reduction in multiple pregnancy rate in donor oocyte-recipient gestational carrier (GC) in vitro fertilization (IVF) cycles in the USA with single-embryo transfer and preimplantation genetic testing. [PDF]

J Assist Reprod Genet, 2021
Makhijani R, Coulter M, Taggar A, Godiwala P, O'Sullivan D, Nulsen J, Engmann L, Benadiva C, Grow D.   +8 more
europepmc   +1 more source