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When multiple primary lung cancers express the same rare mutation: a case report [PDF]

open access: yesFrontiers in Oncology
The debate continues whether the expression of the same rare genetic mutation in multiple primary lung cancers suggests intrapulmonary metastasis or truly multiple primary lung cancers.
Yaqing Han   +8 more
doaj   +4 more sources

Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review [PDF]

open access: yesFrontiers in Oncology, 2022
Multiple primary lung cancers (MPLCs) are that patients with lung cancer may present with two primary tumors at the same time (synchronous multiple primary lung cancer, SMPLC) or may develop a second, metachronous primary lung cancer after treatment of ...
Zhou Huimin   +6 more
doaj   +2 more sources

Small nodules (≤ 6 mm in diameter) of multiple primary lung cancers: prevalence and management [PDF]

open access: yesJournal of Cardiothoracic Surgery, 2022
Background Synchronous multiple primary lung cancers associated with small non-dominant nodules are commonly encountered. However, the incidence, follow-up, and treatment of small non-dominant tumors have been but little studied.
Hua Cheng   +8 more
doaj   +2 more sources

Genetic and immune characteristics of multiple primary lung cancers and lung metastases [PDF]

open access: yesThoracic Cancer, 2021
Background To explore the genetic and immunophenotyping heterogeneities between patients with intrapulmonary metastasis (IPM) or multiple primary lung cancer (MPLC).
Ronghua Yang   +8 more
doaj   +2 more sources

Long-read sequencing and proteomics reveal blood transcriptome and protein expression profiles in multiple primary lung cancers [PDF]

open access: yesBMC Cancer
Multiple primary cancers (MPC) refer to the occurrence of two or more independent primary malignant tumors in the same patient, either simultaneously or metachronously.
Yingkui Huang   +8 more
doaj   +2 more sources

Simultaneous bilateral video-assisted thoracic surgery is safe and feasible for multiple primary lung cancers [PDF]

open access: yesJournal of Cardiothoracic Surgery
Background The treatment for bilateral synchronous multiple primary lung cancers (MPLC) remains challenging. Simultaneous bilateral video-assisted thoracic surgery (VATS) may be an optimal treatment with curative intent, but its safety and feasibility ...
Libing Yang   +6 more
doaj   +2 more sources

Multiple primary lung cancers, the hybrid approach in management: a case report [PDF]

open access: yesJournal of Cardiothoracic Surgery
With improved screening and imaging, multiple primary lung cancers (MPLCs) are being recognized more frequently. Differentiating MPLCs from metastases is crucial for accurate staging and management.
Dana Kanafani   +3 more
doaj   +2 more sources

Using molecular characteristics to distinguish multiple primary lung cancers and intrapulmonary metastases [PDF]

open access: yesPeerJ
Objectives Multiple lung cancers may present as multiple primary lung cancers (MPLC) or intrapulmonary metastasis (IPM) with variations in clinical stage, treatment, and prognosis.
Zhenhua Li   +9 more
doaj   +3 more sources

Synchronous multiple primary lung cancers with shared EGFR mutation but differential imaging findings and pathological subtypes: A case report [PDF]

open access: yesRespiratory Medicine Case Reports, 2020
Lung cancer is a leading cause of cancer mortality worldwide. As the incidence of lung cancer increases in recent years, the number of patients diagnosed with synchronous multiple primary lung cancers (SMPLC) is also rising. SMPLC diagnosis is often made
Lei Su   +5 more
doaj   +2 more sources

Multiple Primary Lung Cancers: A New Challenge in the Era of Precision Medicine [PDF]

open access: yesCancer Management and Research, 2020
Lishu Zhao, Chaoyuan Liu, Guiyuan Xie, Fang Wu, Chunhong Hu Department of Oncology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, People’s Republic of ChinaCorrespondence: Fang Wu; Chunhong HuDepartment of Oncology,
Zhao L, Liu C, Xie G, Wu F, Hu C
doaj   +2 more sources

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