Results 1 to 10 of about 9,608,554 (246)

Unraveling the genetic landscape of susceptibility to multiple primary cancers [PDF]

HGG Advances
Summary: With advances in cancer screening and treatment, there is a growing population of cancer survivors who may develop subsequent primary cancers.
Pooja Middha, Linda Kachuri, Jovia L. Nierenberg, Rebecca E. Graff, Taylor B. Cavazos, Thomas J. Hoffmann, Jie Zhang, Stacey Alexeeff, Laurel Habel, Douglas A. Corley, Stephen Van Den Eeden, Lawrence H. Kushi, Elad Ziv, Lori C. Sakoda, John S. Witte   +14 more
doaj   +4 more sources

Susceptibility Genes Associated with Multiple Primary Cancers. [PDF]

Cancers (Basel), 2023
With advancements in treatment and screening techniques, we have been witnessing an era where more cancer survivors harbor multiple primary cancers (MPCs), affecting approximately one in six patients.
Lu M, Zhang X, Chu Q, Chen Y, Zhang P.
europepmc   +3 more sources

Multiple primary cancers with prostate malignant tumor as the initial diagnosis: a case report [PDF]

Discover Oncology
With the advancement of medical technology and improvements in living standards, the survival time of many cancer patients has been prolonged. However, a significant proportion of these patients develop multiple primary cancers (MPC), which indicates a ...
Kai Yang, Jiatong Zhou
doaj   +2 more sources

Incidence Patterns and Prognostic Impact of Lung‐Involving Multiple Primary Cancers: A 10‐Year Hospital‐Based Cohort Study [PDF]

Thoracic Cancer
Background Multiple primary cancers (MPCs) are increasingly recognized among lung cancer survivors; however, incidence patterns and prognostic impact of lung‐involving MPCs (MPC‐LC) remain incompletely characterized, particularly given substantial ...
Hayoung Kim, Jin‐Hee Kwon, Heyjin Kim, Jin Kyung Lee, Young Jun Hong, Hye‐Ryoun Kim   +5 more
doaj   +2 more sources

Genomic alterations in oral multiple primary cancers [PDF]

International Journal of Oral Science
Oral squamous cell carcinoma (OSCC) is the predominant type of oral cancer, while some patients may develop oral multiple primary cancers (MPCs) with unclear etiology.
Xuan Zhou, Xinjia Cai, Fengyang Jing, Xuefen Li, Jianyun Zhang, Heyu Zhang, Tiejun Li   +6 more
doaj   +2 more sources

Landscapes of synchronous multiple primary cancers detected by next‐generation sequencing [PDF]

FEBS Open Bio, 2022
An increase in the detection rate of multiple primary cancers has been accompanied with declining cancer death rates over the past few decades. However, synchronous multiple primary tumors have gradually increased, and the molecular mechanisms involved ...
Yiru Kong, Jing Li, Hao Lin, Xiaohua Liang, Xinli Zhou   +4 more
doaj   +2 more sources

Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies [PDF]

BMC Medicine, 2022
Background Up to one of every six individuals diagnosed with one cancer will be diagnosed with a second primary cancer in their lifetime. Genetic factors contributing to the development of multiple primary cancers, beyond known cancer syndromes, have ...
Taylor B. Cavazos, Linda Kachuri, Rebecca E. Graff, Jovia L. Nierenberg, Khanh K. Thai, Stacey Alexeeff, Stephen Van Den Eeden, Douglas A. Corley, Lawrence H. Kushi, Regeneron Genetics Center, Thomas J. Hoffmann, Elad Ziv, Laurel A. Habel, Eric Jorgenson, Lori C. Sakoda, John S. Witte   +15 more
doaj   +2 more sources

Higher-order multiple primary cancers and persistent cross-site risk across human papillomavirus-related anatomical sites in the United States: a population-based Surveillance, Epidemiology, and End Results study [PDF]

Preventive Medicine Reports
Objective: Survivors of cancers at human papillomavirus (HPV)-related sites are at increased risk of subsequent malignancies, but the burden and patterns of higher-order (≥3 primaries) multiple primary cancers (MPCs) and long-term cross-site risk ...
Tessho Maruyama, Makoto Kaneko
doaj   +2 more sources

Metachronous multiple primary cancers involving pulmonary non-Hodgkin lymphoma and bladder cancer: a case report [PDF]

Frontiers in Oncology
Multiple primary cancers (MPC) are characterized by the synchronous or metachronous occurrence of two or more distinct histopathological tumor types.
Kunlei Tan, Kunlei Tan, Xiyun Quan, Xiyun Quan, Miduo Tan, Zhijun Han   +5 more
doaj   +2 more sources

Hematological Malignancies With Multiple Primary Cancers: A Rare Case Presentation [PDF]

Case Reports in Hematology
Soudamini Mahapatra, Priyanka Samal, Ashutosh Samal, Tushar Pandey, Naqash Suse, Bhavani Mandava   +5 more
doaj   +2 more sources