Results 131 to 140 of about 9,917,709 (290)

Less Invasive Surgery under VATS for Synchronous Bilateral Lung Cancers [PDF]

, 2002
A patient with synchronous bilateral lung cancer is described. She was successfully treated with less invasive surgery by right S10 wedge resection using Video-assisted thoracic surgery (VATS) and left S6 segmentectomy.
Morinaga, Masafumi, Akamine, Shinji, Muraoka, Masashi, Nagayasu, Takeshi, Oka, Tadayuki, Ayabe, Hiroyoshi   +5 more
core  

Genetic and epigenetic analyses of MBD3 in colon and lung cancer [PDF]

, 2004
MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a
Bader, S A, S A Bader, D J Harrison, Y Zhu, Sa Bader, Harrison, D J, Dj Harrison, Zhu, Y   +7 more
core   +1 more source

Multiple primary cancer with primary lung cancer in 986 autopsy cases.

Haigan, 1986
剖検例986例を対象に, 肺癌を含む重複癌について検討した.肺癌を含む重複癌は28例で, 原発性肺癌206例の13.6%, 全重複癌81例の34.6%を占めていた.平均年齢は64.2才, 男女比は24対4で男性が圧倒的に多かった.組織型では扁平上皮癌10例、腺癌11例、小細胞癌5例, 大細胞癌5例 (肺内多発癌3例を含む) で, 各々の重複癌発生率は13～16%であった.顕性の第2癌15例の発見の糸口は, 胸部レ線異常が8例と多かったが, 7例は肺結核症や転移性肺癌とされた原発性肺癌であった.肺癌を含む重複癌28例の中間生存期間は, 8ヵ月であり, 肺癌先発例では7ヵ月, 後発例では26ヵ月, 後発例の肺癌発症後のそれは4ヵ月で, いずれも有意差を認めた.担癌体における ...
Fukuda, Yasuki, Nakata, Masayuki, Yoneda, Shuuichi, Noguchi, Yukio, Homma, Takeshi, Yoshida, Kiyokazu, Takayama, Shoujirou   +6 more
openaire   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Sequential targeted therapy in synchronous dual-primary lung adenocarcinomas with EGFR and RET alterations: a 5-year follow-up case report

Frontiers in Oncology
With the increasing detection of multiple primary pulmonary nodules, accurately distinguishing between multiple primary lung cancers and intrapulmonary metastasis is crucial for diagnosis and treatment.
Yong-liang Niu, Ying Yang, Xiao-bao Teng, Ming-feng Han, Di-ming Wang   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Blueprint Of Services For Lung Cancer [PDF]

, 1995
Primary lung cancer is the commonest malignant disease in the developed world, and is the most prevalent form of cancer among men over 65 years. It continues to rise in those aged over 75 years. Mortality from lung cancer is increasing in women.
Doyle, Yvonne G.
core  

Multiple independent primary cancers do not adversely affect survival of the lung cancer patient § [PDF]

, 2020
Objective: Diagnosis of multiple independent primary cancers is increasing in many settings. Objectives of this study were to analyze clinical characteristics, organ location, and prognosis associated with the presentation of multiple independent ...
Montserrat Casamitjana, Ana Maria Novoa, Miquel Porta, Rafael Aguiló, Joan Minguella, Francesc Macià   +5 more
core