Results 91 to 100 of about 9,019,411 (282)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Multiple Cutaneous (pre)-Malignancies [PDF]
, 2015 __Abstract__ The three most common cutaneous malignancies are derived from melanocytes and keratinocytes (ordered in decreasing aggressiveness): melanoma, squamous cell carcinoma (SCC) and basal cell carcinoma (BCC).
Leest, R.J.T. (Robert) van der
core +1 more source
Multiple Primary Malignancies in Renal Transplant Recipients: a Single Centre Retrospective Cohort Study [PDF]
, 2018 Background/Aims: Renal transplant recipients are exposed to immunosuppressive treatment which may increase the risk for developing malignancies. Limited data exists concerning the occurrence of multiple primary malignancies (MPM) in renal transplant ...
Kirincich, Jason +7 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Synchronous multiple primary colorectal cancer in patients with extraintestinal malignancies
Сибирский онкологический журналIntroduction. The incidence of colorectal cancer (CRC) is steadily increasing in Russia. Patients with cancers of extra-intestinal malignancies are at increased risk of developing CRC.
V. V. Podolskiy, E. A. Podolskaya
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
[Multiple primary malignancies].
Lijecnicki vjesnik, 2012 Multiple primary malignancies, metachronous or synchronous, in a single patient are relatively rare event with the increase of incidence in recent decades. The aim of this research is to study their incidence in patients hospitalized at the Division of Radiotherapy, Department of Oncology, University of Zagreb, School of medicine, University Hospital ...
Vesna, Bisof +10 more
openaire +1 more source
Multiple primary malignancies. A rare case of five metachronous tumours [PDF]
, 2005 The Authors report on a patient admitted several times for the occurrence of five multiple metachronous primary malignancies (laryngeal carcinoma, endometrial adenocarcinoma, rectal cancerous polyp, Vater papilla carcinoma and transverse colon cancer ...
Stracqualursi, Antonio +5 more
core +1 more source
Synchronous presentation of papillary thyroid carcinoma and Hodgkin lymphoma – a case report
Libri OncologiciMultiple primary malignancies are increasingly detected due to advanced imaging modalities and comprehensive diagnostic protocols. Papillary thyroid carcinoma (PTC) is the most frequent type of thyroid neoplasm with ever-rising incidence.
Matea Prenc +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source