Results 61 to 70 of about 9,019,411 (282)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2020 In Turkish literature there are very few studies regarding multiple primary malignancies (MPM). The aim of this study was to analyze the synchronous and the metachronous malignancies that occurred with a hematologic malignancy.
Nurhilal Buyukkurt +9 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Double Troubles – Managing a Series of Cases with Dual Primary Malignancies
Medical Journal of Dr. D.Y. Patil VidyapeethThe reported incidence of multiple primary malignant tumor (MPMT) is between 0.734% and 11.7%. Double primary malignancy is the occurence of second primary malignant tumor of another organ in patients with a known malignant tumor.
Santhosh Nanjappa +4 more
doaj +1 more source
Update on second primary malignancies in multiple myeloma: a focused review
, 2014 The last decade has seen significant advances in the management of patients with multiple myeloma (MM). With increasingly effective therapies, MM patients are living longer.
Mailankody, S +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Characteristics of multiple primary malignancies in renal cell carcinoma
, 2018 Purpose: This study aimed to evaluate the incidence, nature and prognosis of multiple primary malignancies in renal cell carcinoma. Materials and methods: From June 1995 to April 2004, we retrospectively reviewed the records of 578 patients who underwent
변영준
core +1 more source
Secondary Primary Malignancies in Multiple Myeloma: An Old Nemesis Revisited
Advances in Hematology, 2012 The treatment of myeloma has undergone extraordinary improvements in the past half century. These advances have been accompanied by a concern for secondary primary malignancies (SPMs).
Jay Yang +2 more
doaj +1 more source
Multiple Primary Malignancies and HPV
, 2008 role of HPV in the pathogenesis of multiple ...
DODARO, CONCETTA ANNA +7 more
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