Results 111 to 120 of about 9,060,069 (257)

Multiple primary malignancies involving lung: An analysis of 40 cases

, 2008
We aimed to assess the incidence of multiple primary malignancies in primary lung cancer patients. We retrospectively evaluated the clinical files of 1038 primary lung cancer patients diagnosed in 2004.
Yilmaz, Adnan, Sulu, Ebru, Tuncer, Leyla Yagci, Damadoglu, EBRU, Ertugrul, Muyesser   +4 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

An unusual case of malignancy-related hypercalcemia

, 2013
Mary-Anne Doyle, Janine C Malcolm Division of Endocrinology, University of Ottawa, Ottawa, ON, Canada Objective: To report the case of a 28-year-old woman who presented with hypercalcemia (total calcium =4.11 mmol/L), elevated parathyroid hormone (PTH ...
Doyle MA, Malcolm JC
core  

Multiple concurrent primary extramammary Paget’s disease [PDF]

, 2016
Extramammary Paget’s disease (EMPD) is a rare malignant disorder of the skin, which was described in as early as the nineteenth century. EMPD usually occurs as a single lesion in the apocrine sweat gland–bearing skin with abundant hair follicles. Here,
Norazirah Md Nor, Leelavathi Muthupalaniappen, Nur Amirah binti Amat Puad   +2 more
core  

Characteristics and Outcomes of Second Primary Multiple Myeloma in Adult Cancer Survivors: A Population‐Based Cohort Study

Cancer Medicine
Background This study aimed to investigate characteristics and outcomes of second primary multiple myeloma (2‐MM) stratified by prior primary malignancies (PPMs), and further explore the effect of PPM treatment modalities on multiple myeloma (MM ...
Nannan Li, Jiangping Zeng, Zhixiang Jia, Jinyuan Lu, Yuting Ma, Guangming Wang, Aibin Liang, Wenjun Zhang   +7 more
doaj   +1 more source

Risk for second primary malignancies in patients with multiple myeloma: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundWith improving survival in multiple myeloma (MM), second primary malignancies (SPMs) remain an important issue in long-term care. This study assessed the risk of SPMs among individuals with MM.MethodsWe systematically searched EMBASE, PubMed ...
Yingjie Tian, Yingjie Tian, Liang Su, Yujin Li, Minlan Ye, Yuchu Zhang, Yuchu Zhang, Qiwei Li, Yongzheng Jiao, Jie Wu   +9 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Malignancy risk prediction for primary jejunum-ileal tumors

, 2000
This work is aimed at identifying factors associated with primary jejunum-ileal tumors malignancy, defining a prediction model with sensitivity, specificity and accuracy to distinguish malign from benign neoplasms.
PORTELA Margareth Crisóstomo, MARQUES Ruy Garcia   +1 more
core  

Clinical characteristics and survival of breast cancer patients with extramammary malignancies in a single Asian center over the past 23 years

Discover Oncology
Background The rise of multiple primary malignant neoplasms (MPMNs) necessitates exploration. MPMNs represent 18% of U.S. cancers. Breast cancer is the predominant malignancy among female Americans.
Bei Sun, Yaoyao Jing, Yang Wang, Haiyan Wang, Xinyue Zhang, Jin Zhang, Feng He   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source