Results 51 to 60 of about 940,352 (300)

Involvement of the genitourinary system in multiple primary malignant neoplasms: a review.

, 1983
A case is presented of a patient with separate primaries of the cervix, breast, bladder, and kidney. In a review of 352,073 cancer patients in the literature, the genitourinary system appears to be at a greater risk of this phenomenon.
V Ortolano, R Sharifi, P Ray, P Guinan
core   +1 more source

Multiple metachronous and synchronous malignancies with lung and thorax involvement. Report of two cases

Respiratory Medicine Case Reports, 2018
Multiple primary malignant neoplasms (MPMN) is an uncommon phenomenon, while the diagnosis of such conditions is very significant. Considering that the strategy of the treatment is determined by the histological type of the tumor, practitioners should be
Konstantinos Sapalidis, Nikos Schizas, Achileas Lazopoulos, Parthena Kamparoudi, Dimitris Paliouras, Chrysa Sardeli, Fotis Konstantinou, Fotis Chatzinikolaou, Pavlos Sarafis, Paul Zarogoulidis, Ioanna Kougioumtzi, Nikolaos Katsikogiannis, Ilias Karapantzos, Chrysa Karapantzou, Stella Laskou, Charilaos Koulouris, Stylianos Mantalobas, Dimitris Giannakidis, Isaak Kesisoglou, Nikos Barbetakis   +19 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Characteristics of Multiple Primary Malignant Neoplasms Associated with the Urinary Tract Malignancy [PDF]

, 2001
Purpose: Improvement in the prognosis of multiple primary malignant neoplasm may be attained by early discovery and awareness of the secondary tumor. This study aimed to determine the characteristics of multiple primary neoplasms involving the urinary ...
최영득
core  

Multiple primary malignancies

, 2004
As the incidence and prevalence of cancer increase with age, it is reasonable to expect that the incidence and prevalence of multiple primary malignancies will increase as well.
A. Luciani, L. Balducci
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Analysis of the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in a general hospital

Бюллетень сибирской медицины
Aim. To analyze the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in 2017–2023 in a multidisciplinary inpatient facility.Materials and methods.
M. V. Zavyalova, A. V. Zavyalov, D. S. Pismenny, L. V. Pikalova, L. D. Zhuykova, Yu. M. Zhuykova, M. Yu. Grishchenko, S. V. Vtorushin, N. V. Litvyakov, M. V. Perelmuter   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Neoplasias primárias múltiplas em pacientes com câncer colorretal Multiple primary neoplasms in colorectal cancer patients

, 2000
Introdução - A presença de uma segunda neoplasia maligna, tendo sítio e histologia diferentes da primeira, define o conceito de neoplasias primárias múltiplas.
Marcelo de Souza CURY, Cury, Marcelo De Souza [UNIFESP], Nora Manoukian FORONES, Forones, Nora Manoukian [UNIFESP], CURY, Marcelo de Souza, FORONES, Nora Manoukian   +5 more
core   +1 more source

Metachronous Primary Cerebral Rhabdomyosarcoma After Treatment of Oral Primitive Neuroectodermal Tumor/ Ewing’s Sarcoma in a School-Aged Girl

Philippine Journal of Pathology, 2020
Multiple primary malignancies are defined as two or three malignant neoplasms arising in different organ systems. Several cases of multiple primary malignancies are emerging in recent years due to the advancement in medical therapy and diagnostics ...
Danielle Anne Gonong, Manuelito Madrid
doaj   +1 more source