Results 131 to 140 of about 4,618,210 (296)

Enhancing U-Net for image denoising with bilateral filter noise residue and gradient estimation (BIRUNet)

open access: yesScientific Reports
In recent years, Convolutional Neural Networks (CNNs) have achieved remarkable success in various computer vision tasks, including image denoising. Image denoising focuses on reconstructing a clean image from its noise-corrupted counterpart.
S. Soniya   +3 more
doaj   +1 more source

Robust Space-Object Association and Recursive Estimation for Ground-Based Optical Observation Under Degraded Orbital Priors and Site-Position Uncertainty

open access: yesRemote Sensing
Ground-based optical observation is a key sensing modality for space-object monitoring, but reliable association becomes challenging when orbital priors are degraded, site-position information is imprecise, and each frame contains multiple point-source ...
Tingkai Yan   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Gaussian Process priors with uncertain inputs? Application to multiple-step ahead time series forecasting [PDF]

open access: yes, 2003
We consider the problem of multi-step ahead prediction in time series analysis using the non-parametric Gaussian process model. k-step ahead forecasting of a discrete-time non-linear dynamic system can be performed by doing repeated one-step ahead ...
Quiñonero Candela, J   +13 more
core   +1 more source

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

open access: yesBMC Medical Research Methodology
Background REFRACT is a randomised trial aimed at rapidly evaluating multiple novel therapies against standard treatment for relapsed or refractory follicular lymphoma (rrFL) using a minimal number of patients.
Charlotte Gaskell   +10 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Optimal Stopping with Dynamic Variational Preferences [PDF]

open access: yes
We consider optimal stopping problems in uncertain environments for an agent assessing utility by virtue of dynamic variational preferences or, equivalently, assessing risk by dynamic convex risk measures.
Daniel Engelage
core  

A Bayesian Feature Weighting Model with Simplex-Constrained Dirichlet and Contamination-Aware Priors for Noisy Medical Data

open access: yesMathematics
Feature weighting plays a central role in medical classification by enhancing predictive accuracy, interpretability, and clinical trust through the explicit quantification of variable relevance.
Mehmet Ali Cengiz   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Dynamic Variational Preferences [PDF]

open access: yes
We introduce and axiomatize dynamic variational preferences, the dynamic version of the variational preferences we axiomatized in [21], which generalize the multiple priors preferences of Gilboa and Schmeidler [9], and include the Multiplier Preferences ...
Fabio Maccheroni   +2 more
core  

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