Extending an Anatomy-Aware Framework for Unsupervised Segmentation of Multiple Sclerosis Lesions
Traditional unsupervised lesion segmentation methods focus on modeling the healthy brain distribution, detecting lesions as deviations from it.
Seyedeh-Parisa Zarei +2 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Recursive Multiple-Priors [PDF]
This paper axiomatizes an intertemporal version of multiple-ptiors utility. A central axiom is dynamic consistency, which leads to a recursive structure for utility, to 'rectangular' sets of priors and to prior-by-prior Bayesian updating as the updating ...
Larry G. Epstein, Martin Schneider
core
Joint Luminance-Saliency Prior and Attention for Underwater Image Quality Assessment
Underwater images, as a crucial medium for storing ocean information in underwater sensors, play a vital role in various underwater tasks. However, they are prone to distortion due to the imaging environment, which leads to a decline in visual quality ...
Zhiqiang Lin +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Bayesian model comparison based on expected posterior priors for discrete decomposable graphical models [PDF]
The implementation of the Bayesian paradigm to model comparison can be problematic. In particular, prior distributions on the parameter space of each candidate model require special care.
Guido Consonni, Monia Lupparelli
core
AFAT-MER: Anatomy-guided adaptive transformer for micro-expression recognition
Although existing deep learning-based micro-expression recognition (MER) methods often incorporate facial anatomical structure priors to facilitate feature modeling, such prior knowledge is typically underutilized, applied in a rigid manner, and lacks ...
SHENG Gaojie +7 more
doaj
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Enhanced objective Bayesian testing for the equality of two proportions
We develop a new class of prior distributions for Bayesian comparison of nested models, which we call intrinsic moment priors, by combining the well-established notion of intrinsic prior with the recently introduced idea of non-local priors, and in ...
G. Consonni +4 more
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source

