Results 91 to 100 of about 15,981,515 (305)

Two Scales, One Methodology - Expenditure Based Equivalence Scales for the United States and Germany [PDF]

open access: yes
Choosing an appropriate equivalence scale is a prerequisite for comparisons of economic wellbeing income distribution, inequality or poverty. This is true for country specific work or for cross-national comparisons.
Joachim Merz   +4 more
core  

Solution of Quadratic Nonlinear Problems with Multiple Scales Lindstedt-Poincare Method

open access: yes, 2015
A recently developed perturbation algorithm namely the multiple scales Lindstedt-Poincare method (MSLP) is employed to solve the mathematical models. Three different models with quadratic nonlinearities are considered.
Gözde Sarı, Mehmet Pakdemirli
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Using Virtual Reaction Scheme in the Multiple Time Scales System for Stochastic Modelling

open access: yesApplications of Modelling and Simulation, 2021
A virtual reaction scheme and the notion of quasi-independent is proposed in this paper to assist in model partitioning for the biochemical reactions with multiple time scales.
C. F. Khoo
doaj  

Insertion Method for Multiple Messenger Problem with Multiple Depots

open access: yes, 2015
Messenger problem, as the variation of pickup and delivery problem, deals with the transport of a set of packages from their origins to given destinations.
Jan Fabry
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

A novel method for estimating pathogen presence, prevalence, load, and dynamics at multiple scales

open access: yesScientific Reports
The use of quantitative real-time PCR (qPCR) to monitor pathogens is common; however, quantitative frameworks that consider the observation process, dynamics in pathogen presence, and pathogen load are lacking. This can be problematic in the early stages
John F. Grider   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

An Intelligent Incremental Update Method for Building Data Across Multiple Scales Supported by Categorical Boosting

open access: yesISPRS International Journal of Geo-Information
Leveraging larger-scale data with higher currency to incrementally update smaller-scale data, thereby upholding consistency across multiple scale databases, has become a core focus of contemporary map production tasks centered on data updates.
Xinyu Niu   +6 more
doaj   +1 more source

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