Results 11 to 20 of about 56,774 (264)
Natalizumab for relapsing-remitting multiple sclerosis
Introduction: Natalizumab is a monoclonal antibody that inhibits leukocyte migration across the blood-brain barrier and has been approved for the treatment of relapsing-remitting multiple sclerosis.
A. Horga, M. Tintoré
doaj +3 more sources
Postural Control in Relapsing-Remitting Multiple Sclerosis [PDF]
Introduction Postural instability is considered one of the most disabling symptoms of relapsing-remitting multiple sclerosis (RRMS). Objective To evaluate postural control in patients with RRMS.
Flavia Salvaterra Cusin +5 more
doaj +3 more sources
Interferon in relapsing-remitting multiple sclerosis [PDF]
Recombinant interferons have been shown to suppress both the clinical and magnetic resonance imaging (MRI) measures of disease activity in patients with relapsing remitting multiple sclerosis (RRMS).We performed a Cochrane review of all randomised, placebo-controlled trials of recombinant interferons in RRMS.Of 208 articles identified by a predefined ...
George PA Rice +7 more
openaire +3 more sources
Natalizumab for relapsing remitting multiple sclerosis [PDF]
Natalizumab (NTZ) (Tysabri(®)) is a monoclonal antibody that inhibits leukocyte migration across the blood-brain barrier, thus reducing inflammation in central nervous system, and has been approved worldwide for the treatment of relapsing-remitting multiple sclerosis (RRMS).To evaluate the efficacy, tolerability and safety of NTZ in the treatment of ...
Pucci, Eugenio +6 more
openaire +4 more sources
Rituximab vs Ocrelizumab in Relapsing-Remitting Multiple Sclerosis [PDF]
ImportanceOcrelizumab, a humanized monoclonal antibody targeted against CD20+ B cells, reduces the frequency of relapses by 46% and disability worsening by 40% compared with interferon beta 1a in relapsing-remitting multiple sclerosis (MS). Rituximab, a chimeric monoclonal anti-CD20 agent, is often prescribed as an off-label alternative to ocrelizumab ...
Roos, Izanne +93 more
openaire +6 more sources
EХPERIENCE IN INTERFERON β-1A USE FOR TREATMENT OF MULTIPLE SCLEROSIS IN CHILDREN
Aim: to evaluate the impact of subcutaneous interferon β-1a on matrix metalloproteinases 3, 8, 9 (MMP), cytokines (tumor necrosis factor α — TNF α, and transforming growth factor β1 — TGF β1) levels in serum of children with relapsing-remitting multiple ...
L. M. Kuzenkova +5 more
doaj +1 more source
Progressive multiple sclerosis: Prospects for disease therapy, repair, and restoration of function [PDF]
Multiple sclerosis is a major cause of neurological disability, which accrues predominantly during progressive forms of the disease. Although development of multifocal inflammatory lesions is the underlying pathological process in relapsing-remitting ...
Cohen, JA +3 more
core +1 more source
Background Natalizumab is a monoclonal antibody approved for the treatment of patients with relapsing-remitting multiple sclerosis. According to the current clinical recommendations, its use during pregnancy should be carefully evaluated only in women ...
Elisabetta Godano +8 more
doaj +1 more source
Interferon beta in multiple sclerosis: experience in a British specialist multiple sclerosis centre [PDF]
Background: The efficacy of interferon beta (IFN beta) is well established in relapsing-remitting multiple sclerosis (MS). However, the use of this drug in clinical practice is complex, especially because it is only partially effective, its long term ...
Dubois, B.D. +7 more
core +2 more sources
Intestinal Permeability in Relapsing-Remitting Multiple Sclerosis [PDF]
Changes of intestinal permeability (IP) have been extensively investigated in inflammatory bowel diseases (IBD) and celiac disease (CD), underpinned by a known unbalance between microbiota, IP and immune responses in the gut. Recently the influence of IP on brain function has greatly been appreciated. Previous works showed an increased IP that preceded
Buscarinu, M. C. +13 more
openaire +3 more sources

