Results 161 to 170 of about 6,020,192 (375)

The Incidence of Fever and Leucocytosis in Multiple Sclerosis. (Arch. of Neur. and Psychiat., September, 1930.) McKenna, J. B. [PDF]

, 1931
G. W. T. H. Fleming
openalex   +1 more source

Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Advanced Science, EarlyView.
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan, Xing He, Su Wu, Na Xiong, Xinyu Hou, Heting Wang, Diane Somlo, Martin Spiess, Haiyang Wang, Jifeng Yang, Chunliang Li, Shasha Li, Wenbin Ma, Yanming Chen, Jun Cui, Ling Qi, Guojun Shi   +16 more
wiley   +1 more source

THE CLINICAL PICTURE OF MULTIPLE SCLEROSIS WITH THE PATHOLOGICAL FINDINGS OF ARTERIOSCLEROSIS [PDF]

, 1909
CHARLES K. MILLS, WILLIAM G. SPILLER
openalex   +1 more source

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

Lancet Neurology, 2017
A. Thompson, B. Banwell, F. Barkhof, W. Carroll, T. Coetzee, G. Comi, J. Correale, F. Fazekas, M. Filippi, M. Freedman, K. Fujihara, S. Galetta, H. Hartung, L. Kappos, F. Lublin, R. Marrie, Aaron E Miller, David H. Miller, X. Montalban, E. Mowry, P. Sørensen, M. Tintoré, A. Traboulsee, M. Trojano, B. Uitdehaag, S. Vukusic, E. Waubant, B. Weinshenker, S. Reingold, Jeffrey A. Cohen   +29 more
semanticscholar   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

BULBAR PALSY IN MULTIPLE SCLEROSIS [PDF]

, 1907
Thos. J. Orbison
openalex   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

Advanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du, Akiko Mizokami, Junjun Ni, Simeng Zhang, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Isei Tanida, Takashi Kanematsu   +8 more
wiley   +1 more source

A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]

arXiv
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv  

MULTIPLE SCLEROSIS IN CHILDREN AND ITS RELATION TO ACUTE INFECTIOUS DISEASES [PDF]

, 1891
J W B
openalex   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source