Results 181 to 190 of about 752,420 (346)

Phase I Trial of Intrathecal Mesenchymal Stem Cell-derived Neural Progenitors in Progressive Multiple Sclerosis

open access: yesEBioMedicine, 2018
Background: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system and is one of the leading causes of disability in young adults.
Violaine K. Harris   +7 more
doaj  

Neurophysiological corelates of fatigue and the feasibility of progressive resistance exercise for ameliorating symptoms of fatigue in people with multiple sclerosis [PDF]

open access: yes
Clinicians are continually looking for effective treatments for multiple sclerosis (MS)- fatigue, but this has been hampered by unclear definitions of fatigue and studies of heterogeneous people with MS, including those who are highly-fatigued (MS-HF ...
Ellison, Paula   +1 more
core  

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

open access: yesAdvanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang   +6 more
wiley   +1 more source

Multiple sclerosis: 2024 update. [PDF]

open access: yesFree Neuropathol
Klotz L, Saraste M, Airas L, Kuhlmann T.
europepmc   +1 more source

Plasma phospholipids and their fatty acid composition in multiple sclerosis [PDF]

open access: bronze, 1966
A. Montfoort   +3 more
openalex   +1 more source

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

open access: yesAdvanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng   +14 more
wiley   +1 more source

Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang   +4 more
wiley   +1 more source

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